Results 131 to 140 of about 251,409 (391)
Validity of ICD-9 and ICD-10 codes used to identify acute liver injury: a study in three European data sources [PDF]
, 2019 This is the peer reviewed version of the following article: Forns, J. [et al.]. Validity of ICD-9 and ICD-10 codes used to identify acute liver injury: a study in three European data sources. "Pharmacoepidemiology and drug safety", 6 Juny 2019, vol.
Cainzos Achirica, Miguel +14 more
core +5 more sources
Synthesis of pharmaceutically relevant 17-α-amino steroids using an ω-transaminase.
Chemical Communications, 2014 An efficient and sustainable biocatalytic route for the synthesis of important 17-α-amino steroids has been developed using an ω-transaminase variant from Arthrobacter sp.
Nina Richter +4 more
semanticscholar +1 more source
Emerging Therapeutic Strategies for Hearing Loss
Advanced Therapeutics, EarlyView.Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han +9 more
wiley +1 more source
Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery
Advanced Science, EarlyView.Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou +8 more
wiley +1 more source
Use of OKT3 with ciclosporin and steroids for reversal of acute kidney and liver allograft rejection [PDF]
, 1987 OKT3 monoclonal antibody therapy was added to preexisting baseline immunosuppressive treatment with ciclosporin and steroids to treat rejection in 52 recipients of cadaveric livers and 10 recipients of cadaveric kidneys.
Demetris, AJ, Fung, JJ, Porter, KA
core +1 more source
Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies
Advanced Science, EarlyView.Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu +7 more
wiley +1 more source
Integrative Medicine Research, 2017 Background: The use of plants and plant products for medicinal purposes is an age-long practice in traditional communities and is becoming prominent globally.
Stanley Anyanwu +5 more
doaj +1 more source
HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox". [PDF]
, 2016 BackgroundProprotein convertase subtilisin kexin 9 (PCSK9) inhibitors reduce low-density lipoprotein cholesterol (LDL-C) and improve outcomes in the general population.
Deeks, Steven +10 more
core +1 more source
Advanced Science, EarlyView.sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin +21 more
wiley +1 more source