Results 151 to 160 of about 137,846 (394)

Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation. [PDF]

, 2016
Commercial dietary supplements are marketed as a panacea for the morbidly obese seeking sustainable weight-loss. Unfortunately, many claims cited by supplements are unsupported and inadequately regulated.
Bodzin, Adam S, Busuttil, Ronald W, Lunsford, Keri E, Reino, Diego C, Wang, Hanlin L   +4 more
core   +1 more source

Muscular Dystrophy and Transaminases

The Journal of Kartal Training and Research Hospital, 2014
Bulgular: Yaslari 5-10 yas arasi olan 11 cocuk degerlendirildi. Hastalarin 9’u erkek (%81.8) ve 2’si (%18.2) kiz idi. Fizik muayenede tum cocuklarin boy ve kilosu 3. persentilin uzerinde ve hepsinin norolojik gelisimi normal bulundu. Bes erkek cocukta (%45.5) gastroknemius kasinda hipertrofi saptandi. ALT seviyesi 70-2400 IU/L arasinda, AST seviyesi 70-
Meltem Ugras, Canan Kocaman Yıldırım, Ayça Vitrinel, Öznur Küçük   +3 more
openaire   +2 more sources

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao, Lin Zeng, Jiaren Wang, Chang Hong, Ziyong Zhang, Chengkai Wu, Hao Cui, Yan Li, Ruining Li, Shengxing Liang, Qijie Deng, Wenyuan Li, Xuejing Zou, Pengcheng Ma, Li Liu   +14 more
wiley   +1 more source

Serum Lactic Dehydrogenase and Serum Transaminase in Human Leukemia [PDF]

, 1959
Gordon B. Magill, Felix Wróblewski, John S. LaDue   +2 more
openalex   +1 more source

Structural Basis of the Substrate Range and Enantioselectivity of Two (S)-Selective ω-Transaminases.

Biochemistry, 2016
ω-Transaminases are enzymes that can introduce an amino group in industrially interesting compounds. We determined crystal structures of two (S)-selective ω-transaminases, one from Arthrobacter sp.
N. van Oosterwijk, Simon C. Willies, J. Hekelaar, A. C. Terwisscha van Scheltinga, N. Turner, B. Dijkstra   +5 more
semanticscholar   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Improvement of neutropenia in 2 adolescent cases treated with empagliflozin for glycogen storage disease type Ib [PDF]

Pediatric Emergency Medicine Journal
Neutropenia and elevated concentrations of hepatic transaminases often lead to referrals from emergency or outpatient departments to relevant specialists to diagnose underlying inborn errors of metabolism.
Hyunwoo Bae
doaj   +1 more source

Cytogenetic, Hematobiochemical, and Histopathological Assessment of Albino Rats (Rattus norvegicus) Fed on Gluten Extracts [PDF]

arXiv
Background: Literature shows that most of the information on the toxicity of gluten is generated from survey and observational studies, resulting in inconsistent outcomes and a decrease in the acceptability of gluten-rich foods. To determine gluten's safety, an in-depth in vitro and in vivo toxicological examination is required. This enables scientists
arxiv  

Asymmetric Biocatalytic Synthesis of Fluorinated Pyridines through Transesterification or Transamination: Computational Insights into the Reactivity of Transaminases

, 2017
The synthesis of a family of pyridines bearing a fluorinated substituent on the aromatic ring has been carried out through two independent and highly stereoselective chemoenzymatic strategies.
M. Lopez-Iglesias, Daniel González‐Martínez, María Rodríguez-Mata, V. Gotor, E. Busto, W. Kroutil, V. Gotor‐Fernández   +6 more
semanticscholar   +1 more source

Efficient and Specific PDGFRβ‐Targeting Dual‐Mode T1‐T2 MRI Nanoprobe for Early Diagnosis of Non‐Alcoholic Fatty Liver

Advanced Science, EarlyView.
The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li, Tongwei Zhang, Tongxiang Tao, Yaxuan Liu, Haining Xia, Sajid ur Rehman, Zeyong Guo, Jing Zhang, Ruiguo Chen, Zhan Zhang, Junfeng Wang, Kun Ma   +11 more
wiley   +1 more source