Results 71 to 80 of about 77,314 (347)

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Advanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang   +8 more
wiley   +1 more source

Monitoramento de eletrólitos, de marcadores de danos musculares e função renal em atletas de Futebol de Elite

Revista Brasileira de Nutrição Esportiva, 2018
O monitoramento de marcadores bioquímicos é necessário para conhecer o estado orgânico de atletas diante da rotina extenuante de treinamento e competição.
Bruna Krefta, Caroline Vechi, Flavia Gabriela Pinezi, Thais Regina Mezzomo   +3 more
doaj  

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Fatal lymphoproliferation and acute monocytic leukemia-like disease following infectious mononucleosis in the elderly [PDF]

, 1981
Three elderly patients are reported, in whom serologically confirmed recent infectious mononucleosis is followed by fatal lymphoproliferation (case 1), by acute monocytic leukemia (case 2), and by acute probably monocytic leukemia (case 3)
Deinhardt, F., Hehlmann, R., Schmid, M., Walther, B., Wolf, Hans J., Zöllner, N.   +5 more
core   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

La stéatose hépatique métabolique liée à l´obésité chez l´adulte Burkinabè

The Pan African Medical Journal, 2021
INTRODUCTION: La stéatopathie métabolique est-elle une priorité de santé en Afrique? Le but était d´étudier les facteurs épidémiologiques et les manifestations hépatiques (anomalies biologiques et la stéatose échographique) associés au syndrome ...
Nômawendé Inès Compaoré, Aboubacar Coulibaly, Mali Koura, Kounpiélimé Sosthène Somda, Couna Christiane Somé, Nadine Marie Stella Zombré, Alain Bougouma   +6 more
doaj   +1 more source

Statin therapy in critical illness : an international survey of intensive care physicians' opinions, attitudes and practice [PDF]

, 2012
Background Pleotropic effects of statins on inflammation are hypothesised to attenuate the severity of and possibly prevent the occurrence of the host inflammatory response to pathogen and infection-related acute organ failure.
Di Gangi, Stefania, Kruger, Peter S., McAuley, Danny F., Perkins, Gavin D., Scales, Damon C., Shankar-Hari, Manu, Terblanche, Marius   +6 more
core   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

Hepatitis reactive to Dengue virus

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
This is a case of a 43-year-old female physician, who was admitted to the hospital due to clinical suspected dengue with skin hemorrhage (group 2).
Sarah María Regueira Betancourt, Manuel de Jesús Díaz Pérez   +1 more
doaj  

Seroprevalence and biochemical parameters among patients with Chikungunya in Adamaoua region, Cameroon: A cross‐sectional study

Public Health Challenges
Background Chikungunya virus (CHIKV) infection is a vector‐borne febrile illness endemic to Africa. In Cameroon, few studies have documented human exposure to CHIKV, especially in the Adamaoua region.
Lise Paule Djamko Toko, Borris Rosnay Galani Tietcheu, Ilyassa Dieudonné Tembar, Pascal Dieudonne Chuisseu Djamen, Nicolas Njintang Yanou   +4 more
doaj   +1 more source