Results 81 to 90 of about 77,314 (347)

Association of Serum Iron Parameters with Activity of Liver Enzymes in Mongolian Patients with Chronic Hepatitis "C"

open access: yesCentral Asian Journal of Medical Sciences, 2017
Objectives: The purpose of this study was to investigate the relationship between serum iron parameters with the activity of liver enzymes among patients with HCV in Mongolia.
Uugantsetseg Ganbold   +2 more
doaj   +1 more source

Reduced lysosomal acid lipase activity: A new marker of liver disease severity across the clinical continuum of non-alcoholic fatty liver disease? [PDF]

open access: yes, 2019
Lysosomal acid lipase (LAL) plays a key role in intracellular lipid metabolism. Reduced LAL activity promotes increased multi-organ lysosomal cholesterol ester storage, as observed in two recessive autosomal genetic diseases, Wolman disease and ...
Angelico, F   +7 more
core   +1 more source

Salt‐Compact Albumin as a New Pure Protein‐based Biomaterials: From Design to In Vivo Studies

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A new class of materials built entirely of native albumin protein is designed using a simple protocol based on salt‐assisted compaction, breaking with current crosslinking strategies. This green process leads, surprisingly, to water‐insoluble handable materials with high preservation of their native protein structures and Young's modulus close to that ...
Eya Aloui   +19 more
wiley   +1 more source

Coordinated Slowing of Metabolism in Enteric Bacteria under Nitrogen Limitation: A Perspective [PDF]

open access: yesarXiv, 2001
It is natural to ask how bacteria coordinate metabolism when depletion of an essential nutrient limits their growth, and they must slow their entire rate of biosynthesis. A major nutrient with a fluctuating abundance is nitrogen. The growth rate of enteric bacteria under nitrogen-limiting conditions is known to correlate with the internal concentration
arxiv  

Phenotypical heterogeneity linked to adipose tissue dysfunction in patients with type 2 diabetes [PDF]

open access: yes, 2016
Adipose tissue (AT) inflammation leads to increased free fatty acid (FFA) efflux and ectopic fat deposition, but whether AT dysfunction drives selective fat accumulation in specific sites remains unknown.
ANGELICO, Francesco   +12 more
core   +1 more source

Dual‐Functional Hafnium Oxide Nanoplatform Combining High‐Z Radiosensitization With Bcl‐2 Gene Silencing for Enhanced Cancer Radiotherapy

open access: yesAdvanced Healthcare Materials, EarlyView.
A dual‐functional hafnium oxide nanoplatform is developed for enhanced cancer radiotherapy. This innovative system combines the inherent radiosensitizing properties of high‐Z hafnium oxide with Bcl‐2 gene‐silencing capabilities. The nanoplatform demonstrated synergistic enhancement of radiotherapy efficacy through increased generation of reactive ...
Seungyong Shin   +12 more
wiley   +1 more source

HGF/c‐Met Axis‐Targeted Nanotherapy via GSH‐Responsive Polymer Platforms Suppresses Uveal Melanoma Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
To suppress uveal melanoma metastasis (UM), the GSH‐responsive polymer named NP@Oxa/Criz has been successfully prepared. NP@Oxa/Criz selectively accumulates in UM tumors, targeting HGF/c‐Met Axis to undermine the stemness and metastasis of UM while triggering immunogenic cell death through DAMPs release to boost anti‐tumor immunity.
Hui Tao   +8 more
wiley   +1 more source

Hepatitis B in Pediatric Population: Observational Retrospective Study in Romania

open access: yesLife
Hepatitis B virus (HBV) is a frequent cause of chronic hepatitis worldwide, with an estimated 5.6 million children under 5 years being infected. In Romania, there are no available epidemiology reports on large cohorts in children.
Daniela Păcurar   +4 more
doaj   +1 more source

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang   +10 more
wiley   +1 more source

The interaction between diabetes, body mass index, hepatic steatosis, and risk of liver resection: insulin dependent diabetes is the greatest risk for major complications [PDF]

open access: yes, 2014
Background. This study aimed to assess the relationship between diabetes, obesity, and hepatic steatosis in patients undergoing liver resection and to determine if these factors are independent predictors of major complications.
Aroori, S   +5 more
core   +3 more sources

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