Results 131 to 140 of about 1,943 (192)

Studies on the Transcobalamins

British Journal of Haematology, 1973
Summary. Vitamin B12 absorbed from the gut is transported on all the vitamin B12 binding proteins (transcobalamins) and not primarily on Transcobalamin II. Absorbed vitamin B12 can still be detected on the vitamin B12 binding proteins after 10 days suggesting that the very rapid plasma clearance of the TCII‐vitamin B12 complex previously reported was ...
J M, England, H G, Clarke, M C, Down, I, Chanarin   +3 more
openaire   +3 more sources

The Transcobalamins in Polycythaemia Vera

Scandinavian Journal of Haematology, 1977
The unsaturated B12 binding capacity (UBBC) of the serum and the binding capacity of each of the 3 vitamin B12 binders ‐ the transcobalamins (TC) I, II and III were determined in 21 patients with polycythaemia vera (PV) during the course of the disease and following treatment, using the recently described charged cellulose filter technique.High serum ...
B, Rachmilewitz, N, Manny, M, Rachmilewitz   +2 more
openaire   +3 more sources

Serum Transcobalamins in Healthy Nigerian Children

Acta Haematologica, 1982
The unsaturated vitamin B12-binding capacity (UB12BC) and the three transcobalamins (TC I, TC II, TC III) have been studied in the serum of normal healthy Nigerian children. The serum UB12BC level was very high in the children: TC I accounted for 39.5% of UB12BC, TC II accounted for 49.5% and TC III accounted for 11%.
B O, Osifo, Y, Parmentier, P, Gerard, J P, Nicolas   +3 more
openaire   +3 more sources

On the Origin of Transcobalamins

New England Journal of Medicine, 1977
J, Zittoun, R, Zittoun
openaire   +3 more sources

Transcobalamin Polymorphism and Serum Holo-Transcobalamin in Relation to Alzheimer’s Disease

Dementia and Geriatric Cognitive Disorders, 2004
Isoforms of the vitamin B₁₂ carrier protein transcobalamin (TC) might influence its cellular availability and contribute to the association between disrupted single-carbon metabolism and Alzheimer’s disease (AD). We therefore investigated the relationships between the TC 776C>G (Pro259Arg) genetic polymorphism, total serum ...
McCaddon, Andrew, Bleenow, Kaj, Hudson, Peter R., Hughes, Alan, Barber, Joan, Gray, Rob, Davies, Gareth K., Williams, John H. H., Duguid, Jennifer, Lloyd, Alwyn, Tandy, Steve, Everall, Marge, Cattell, Howard, McCaddon, Anne, Ellis, Dick, Palmer, Mona, Bogdanovic, Nenad, Gottfires, Carl-Gerhard, Zetterberg, Henrik, Rymo, Lars, Regland, Björn   +20 more
openaire   +3 more sources

First trimester serum levels of the soluble transcobalamin receptor, holo-transcobalamin, and total transcobalamin in relation to preeclampsia risk

Scandinavian Journal of Clinical and Laboratory Investigation, 2016
Human placenta expresses CD320, a receptor that ensures the uptake of holo-transcobalamin (holoTC). Soluble CD320 (sCD320) is present in the circulation and its concentration increases during pregnancy.To investigate a possible association of sCD320, holoTC and total transcobalamin (TC) with the risk of subsequent preeclampsia using serum samples from ...
Abuyaman, Omar, Torring, Niels, Obeid, Rima, Nexo, Ebba   +3 more
openaire   +3 more sources

Transcobalamin polymorphism and homocysteine

Blood, 2001
Namour et al[1][1] suggest that codon 259 of the transcobalamin (TC) gene is a major determinant of TC polymorphism in Caucasians and that heterozygous individuals have higher plasma homocysteine.
Andrew McCaddon, Kaj Blennow, Peter Hudson, Björn Regland, Diane Hill   +4 more
openaire   +1 more source

Three family members with elevated plasma cobalamin, transcobalamin and soluble transcobalamin receptor (sCD320)

Clinical Chemistry and Laboratory Medicine, 2013
Plasma cobalamin is requested in order to diagnose cobalamin deficiency and low levels confirm a deficient state. Here, we present three family members with unexpected high levels of cobalamin.We included a patient referred for cobalamin measurement due to neurological symptoms, her son and her daughter.
Hoffmann-Lücke, Elke, Arendt, Johan F B, Nissen, Peter H, Mikkelsen, Gustav, Aasly, Jan O, Nexo, Ebba   +5 more
openaire   +3 more sources