Results 271 to 280 of about 3,599,350 (306)
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Nucleosomes and transcription: recent lessons from genetics
Current Opinion in Genetics & Development, 1997Substantial evidence exists that nucleosomes affect transcription and that additional factors modify nucleosome function. Recent work has demonstrated that different types of histone mutants can be classified by their distinct effects on transcription in vivo.
G A, Hartzog, F, Winston
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Transcription control reprogramming in genetic backup circuits
Nature Genetics, 2005A key question in molecular genetics is why severe mutations often do not result in a detectably abnormal phenotype. This robustness was partially ascribed to redundant paralogs that may provide backup for one another in case of mutation. Mining mutant viability and mRNA expression data in Saccharomyces cerevisiae, we found that backup was provided ...
Kafri, R., Bar-Even, A., Pilpel, Y.
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Genetic dissection of transcriptional regulation by cDNA‐AFLP
The Plant Journal, 2006SummaryThis study demonstrates that cDNA‐AFLP is a powerful gel‐based genome‐scale transcript profiling technique to generate quantitative gene expression profiles for eQTL mapping. We used cDNA‐AFLP to monitor the relative abundance of 912 transcripts across 50 Arabidopsis thaliana recombinant inbred lines.
Marnik, Vuylsteke +4 more
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[Transcriptional abnormalities and genetic testing].
Medecine sciences : M/S, 2005There is a rapidly growing literature on transcription abnormalities, e.g. differential expression of alleles and the role of some single nucleotide polymorphisms in altering splicing patterns. An average 10% of splicing mutations is reported in the Human Gene Mutation Database but this figure could climb to 50% for some genes such as NF1 or ATM.
Claude, Houdayer +1 more
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Genetics of Energetics: Transcriptional Responses in Cardiac Metabolism
Annals of Biomedical Engineering, 2000Recent evidence suggests that energy substrate metabolism forms the link between gene expression and contractile function of the heart. This hypothesis draws on three seemingly unconnected observations, made in 1941 by three different investigators. The first gave rise to the concept of the dynamic nature of body constituents, the second to the concept
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Genetic testing in prostate cancer management: Considerations informing primary care
Ca-A Cancer Journal for Clinicians, 2022Mary-Ellen Taplin +2 more
exaly
Studies on Genetic Transcription
Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite Naturwissenschaftliche Abteilung: Allgemeine, Landwirtschaftliche und Technische Mikrobiologie, 1975R.K. Kakkar, B.R. Mehrotra
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A saturated map of common genetic variants associated with human height
Nature, 2022Nancy Heard-Costa +2 more
exaly