Results 261 to 270 of about 1,566,033 (293)

Model genetic circuits encoding autoregulatory transcription factors

Journal of Theoretical Biology, 1995
Multiple steady-state levels of autoregulatory transcription factors are capable of specifying alternative heritable phenotypes of a cell or an organism. Switching among steady states can result in long-term phenotypic change. In this paper, six model genetic circuits are presented, each encoding a set of autoregulatory transcription factors.
openaire   +2 more sources

[Transcriptional abnormalities and genetic testing].

Medecine sciences : M/S, 2005
There is a rapidly growing literature on transcription abnormalities, e.g. differential expression of alleles and the role of some single nucleotide polymorphisms in altering splicing patterns. An average 10% of splicing mutations is reported in the Human Gene Mutation Database but this figure could climb to 50% for some genes such as NF1 or ATM.
Claude, Houdayer, Dominique, Stoppa-Lyonnet   +1 more
openaire   +1 more source

Chemical-genetics refines transcription factor regulatory circuits

Trends in Cancer
Transcriptional dysregulation is a key step in oncogenesis, but our understanding of transcriptional control has relied on genetic approaches that are slow and allow for compensation. Chemical-genetic approaches have shortened the time frame for the analysis of transcription factors from days or weeks to minutes.
Hillary M. Layden, Anna E. Johnson, Scott W. Hiebert   +2 more
openaire   +2 more sources

Studies on Genetic Transcription

Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite Naturwissenschaftliche Abteilung: Allgemeine, Landwirtschaftliche und Technische Mikrobiologie, 1975
R.K. Kakkar, B.R. Mehrotra
openaire   +1 more source

Genetic testing in prostate cancer management: Considerations informing primary care

Ca-A Cancer Journal for Clinicians, 2022
Veda N Giri, Todd M Morgan, David Morris
exaly  

Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

Missed therapeutic and prevention opportunities in women with BRCA‐mutated epithelial ovarian cancer and their families due to low referral rates for genetic counseling and BRCA testing: A review of the literature

Ca-A Cancer Journal for Clinicians, 2017
Paul J Hoskins, Walter H Gotlieb
exaly  

Genetics of Transcription Factor Mutations

2007
Vijaya Ramachandran, D. Woodrow Benson
openaire   +1 more source

Cancer Epigenetics

Ca-A Cancer Journal for Clinicians, 2010
Jean-Pierre J Issa
exaly  

Pharmacogenetics and pharmacogenomics of anticancer agents

Ca-A Cancer Journal for Clinicians, 2009
R Stephanie Huang, Mark J Ratain
exaly