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A Novel Nonsense Variant in TBX15 Transcription Factor Suggests an Expanded Genetic Spectrum Of Submucous Cleft Palate. [PDF]

Int Dent J
Wang Y, Yu K, Huang L, Cheng Y, Fu X, Ji Y.   +5 more
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Genetics in Light of Transcriptional Adaptation

Trends in Genetics, 2020
Genetics has recently benefited from the genome engineering revolution: genes can be knocked out, knocked down, or activated more easily than ever before. This range of genetic manipulations has also provided a range of outcomes, sometimes contradictory. But how much interesting biology hides within these discrepancies?
Kontarakis, Zacharias, Stainier, Didier Y.R.   +1 more
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The quantitative genetics of transcription

Trends in Genetics, 2005
Quantitative geneticists have become interested in the heritability of transcription and detection of expression quantitative trait loci (eQTLs). Linkage mapping methods have identified major-effect eQTLs for some transcripts and have shown that regulatory polymorphisms in cis and in trans affect expression.
Gibson, Greg, Weir, Bruce
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Visualization of Genetic Transcription

1973
Transcription of structural genes by RNA polymerase to produce messenger RNAs (mRNAs) and the translation of such messengers by polyribosomes to produce proteins are intimately coupled processes in bacterial cells (1). In fact, it is possible to reconstruct coupled transcription and translation systems in vitro from separated bacterial components (2,3).
B A, Hamkalo, O L, Miller
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Genetic transcription

Proceedings of the Royal Society of London. Series B. Biological Sciences, 1966
The purine and pyrimidine base sequence of DNA , permanent repository of the genetic information, must be transcribed on to ribopolynucleotides before genotype can be translated into phenotype. This transcription gives rise to three recognizably different classes of RNA molecules: (1) two ...
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Tissue Specificity of Genetic Transcription

1972
The basic biochemical differences which exist between cells in animal tissues are reflections of characteristic patterns of proteins. The process (es) of differentiation, therefore, may be described as the process (es) whereby cells, presumably of identical genotype, develop into phenotypically distinct entities which reflect characteristic patterns of
R B, Church, I R, Brown
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