Results 171 to 180 of about 2,601,708 (287)

Nonlinear transcriptional responses to gradual modulation of transcription factor dosage. [PDF]

Elife
Domingo J, Minaeva M, Morris JA, Ghatan S, Ziosi M, Sanjana NE, Lappalainen T.   +6 more
europepmc   +1 more source

Terminal Renal Failure in Mice Lacking Transcription Factor AP-2β [PDF]

, 2003
Markus Moser, Sandra DAHMEN, Reinhart Kluge, H.-J. Gröne, Judith Dahmen, Dagmar Kunz, Hubert Schorle, Reinhard Buettner   +7 more
openalex   +1 more source

Inferring functional transcription factor-gene binding pairs by integrating transcription factor binding data with transcription factor knockout data [PDF]

, 2013

core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcription factor c-Maf: a checkpoint that programs autoimmunity. [PDF]

Front Immunol
Liu N, Zhang J, Wang P, Jin S, Yang C, Yan X, Xu J, Wang H, Sun W, Xu D.   +9 more
europepmc   +1 more source

Different papillomaviruses have different repertoires of transcription factor binding sites: convergence and divergence in the upstream regulatory region [PDF]

, 2006
Santiago Garcı́a-Vallvé, José R. Iglesias-Rozas, Ángel Barajas, Ignacio G. Bravo   +3 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Transcription Factor PFB1 Is Required for the Botrytis cinerea Effector BcSCR1-Mediated Pathogenesis. [PDF]

Mol Plant Pathol
Li X, Xie Y, Wen Q, Liu J, Kang J, Qian X, Chen X, Wang J, Yang Y.   +8 more
europepmc   +1 more source

Characterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1 [PDF]

, 2008
Barbara Maenz, Paul Hekerman, Eva M. Vela, Joan Galcerán, Walter Becker   +4 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source