Transcription factor Etv3 controls the tolerogenic function of dendritic cells. [PDF]
Adams NM +19 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Loss of oligodendrocyte transcription factor 2 protein expression in metabolically stressed oligodendrocytes. [PDF]
Kaddatz H +11 more
europepmc +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
GRAS Transcription Factor WLG3 Regulates Grain Size and Weight in Rice. [PDF]
Pan H +9 more
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Metamorphosing macrophages promote placental fibrosis by upregulating the transcription factor STAT5A. [PDF]
Chen A, Huang X, Liao E, Shao Y.
europepmc +1 more source
Inferring functional transcription factor-gene binding pairs by integrating transcription factor binding data with transcription factor knockout data [PDF]
core +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
The transcription factor EHF promotes the maturation and immunosuppression of conventional dendritic cells. [PDF]
Liu X +10 more
europepmc +1 more source

