Results 211 to 220 of about 15,541,955 (379)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster+3 more
wiley +1 more source
Editorial: Bacterial transcription factors and the cell cycle, volume II
Morigen+4 more
doaj +1 more source
Defining transcription factor nucleosome binding with Pioneer-seq. [PDF]
Tsompana M+4 more
europepmc +1 more source
Transcription elongation factor SII interacts with a domain of the large subunit of human RNA polymerase II. [PDF]
Jay Rappaport+5 more
openalex +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla+15 more
wiley +1 more source
Inferring functional transcription factor-gene binding pairs by integrating transcription factor binding data with transcription factor knockout data [PDF]
core +1 more source
MatInspector and beyond: promoter analysis based on transcription factor binding sites
Cartharius K+9 more
semanticscholar +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici+8 more
wiley +1 more source