Results 211 to 220 of about 15,541,955 (379)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Editorial: Bacterial transcription factors and the cell cycle, volume II

open access: yesFrontiers in Microbiology, 2023
Morigen   +4 more
doaj   +1 more source

Defining transcription factor nucleosome binding with Pioneer-seq. [PDF]

open access: yesPLoS Genet
Tsompana M   +4 more
europepmc   +1 more source

Transcription elongation factor SII interacts with a domain of the large subunit of human RNA polymerase II. [PDF]

open access: green, 1988
Jay Rappaport   +5 more
openalex   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla   +15 more
wiley   +1 more source

REPROGRAMMING ZFP189 TRANSCRIPTION FACTOR FUNCTION REGULATES DRUG SPECIFIC BEHAVIORAL RESPONSES AND TRANSCRIPTION

open access: yesIBRO Neuroscience Reports, 2023
Joseph Picone   +5 more
doaj   +1 more source

MatInspector and beyond: promoter analysis based on transcription factor binding sites

open access: yesBioinform., 2005
Cartharius K   +9 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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