Results 221 to 230 of about 1,572,227 (290)

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

DNA methylation shapes transcription factor binding beyond canonical CpG contexts. [PDF]

Proc Natl Acad Sci U S A
Miodownik I, Solozabal R, O'Hagan MP, Albeck S, Peleg Y, Takac M, Afek A.   +6 more
europepmc   +1 more source

A role for the transcription factor Mca1 in activating the meiosis-specific copper transporter Mfc1

, 2018
Jude Beaudoin, Raphaël Ioannoni, Vincent Normant, Simon Labbé   +3 more
openalex   +2 more sources

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Transcription factor activity-based stratification reveals prognostic subtypes and immune landscape in neuroblastoma. [PDF]

Transl Pediatr
Gao M, Li X, Xia Y, Tian X, Li J, Zhang L, Zhao N, Liu Y, Zhao Q.   +8 more
europepmc   +1 more source

ConBind: motif-aware cross-species alignment for the identification of functional transcription factor binding sites

, 2015
Stefan H. Lelieveld, Judith Schütte, Maurits Dijkstra, Punto Bawono, Sarah Kinston, Berthold Göttgens, Jaap Heringa, Nicola Bonzanni   +7 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Tetramerisation governs SALL transcription factor function in development and disease

Giuliani S, Chhatbar K, Wear M, Guy J, Mathieson T, Burdett H, George L, Alston G, Spanos C, McHugh T, Kelly D, Pantier R, Bird A.   +12 more
europepmc   +1 more source

Transcription Factors

The Journal of Steroid Biochemistry and Molecular Biology, 1998
openaire   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source