Results 231 to 240 of about 1,572,227 (290)

An MYB transcription factor regulates capsaicinoid biosynthesis during pepper fruit ripening. [PDF]

BMC Plant Biol
Zhang M, Han S, Wang Z, Luo Z, Chen X, Fang G, Xie Q, Deng M, Lv J.   +8 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

The transcription factor CUX1 exerts opposing roles in human and mouse adipocyte differentiation. [PDF]

Mol Metab
Chen Y, Liu L, Calhoun RP, Cheng L, Steger D, Seale P.   +5 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Transcription factor with ambivalent role - Ralstonia eutropha's PhaR is a repressor of the phasin-gene phaP1 and an activator of phaP3. [PDF]

BMC Microbiol
Cornehl P, Santolin L, Clerc N, Riedel SL, Neubauer P, Gimpel M.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The transcription factor BCL11A restores differentiation potential to aged oligodendrocyte progenitor cells

Ghosh T, Baror R, Zhao C, Sharma A, Goldman N, Franklin RJ.   +5 more
europepmc   +1 more source

Recent Advances in Transcription Factor-Mediated Regulation of Salvianolic Acid Biosynthesis in <i>Salvia miltiorrhiza</i>. [PDF]

Plants (Basel)
Chen S, Peng F, Tao S, Wan X, Liao H, Wang P, Yuan C, Mao C, Zhao X, Zhang C, He B, Zhong M.   +11 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Identification of KHS-101 as a Transcription Factor EB Activator to Promote α-Synuclein Degradation. [PDF]

Int J Mol Sci
Zhu H, Ren A, Li T, Zhou T, Li A, Pan X, Chen L, Chen J.   +7 more
europepmc   +1 more source