Results 231 to 240 of about 15,248,084 (403)

The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR

open access: yesCurrent Biology, 2016
Christopher J. Fiorese   +5 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Decoy-PROTAC for specific degradation of "Undruggable" STAT3 transcription factor. [PDF]

open access: yesCell Death Dis
Li S   +10 more
europepmc   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, Volume 15, Issue 7, Page 1124-1143, July 2025.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Regulatory T cell lineage specification by the forkhead transcription factor foxp3.

open access: yesImmunity, 2005
J. Fontenot   +5 more
semanticscholar   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, Volume 15, Issue 7, Page 1144-1158, July 2025.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

A transcription factor module mediating C<sub>2</sub> photosynthesis in the Brassicaceae. [PDF]

open access: yesEMBO Rep
Dickinson PJ   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy