Results 51 to 60 of about 15,541,955 (379)
Functional Profiling of Transcription Factor Genes in Neurospora crassa. [PDF]
, 2017 Regulation of gene expression by DNA-binding transcription factors is essential for proper control of growth and development in all organisms. In this study, we annotate and characterize growth and developmental phenotypes for transcription factor genes ...
Bekman, Thomas +17 more
core +1 more source
Smad transcription factors [PDF]
Genes & Development, 2005 Smad transcription factors lie at the core of one of the most versatile cytokine signaling pathways in metazoan biology—the transforming growth factor-β (TGFβ) pathway. Recent progress has shed light into the processes of Smad activation and deactivation, nucleocytoplasmic dynamics, and assembly of transcriptional complexes.
Joan Massagué +2 more
openaire +2 more sources
Identification of transcription factor binding sites in promoter databases [PDF]
, 2011 Transcription factors (TFs) are the proteins which regulates the expression of their target genes either in a positive or negative manner. TFs realize this task by binding to a specific DNA sequence contained in promoter regions, via their DNA binding ...
Dağ, Uğur +5 more
core +1 more source
Transcription Factor Networks in Drosophila melanogaster
Cell Reports, 2014 Specific cellular fates and functions depend on differential gene expression, which occurs primarily at the transcriptional level and is controlled by complex regulatory networks of transcription factors (TFs).
David Y. Rhee +12 more
doaj +1 more source
Identification of transcription factor binding sites using ATAC-seq
Genome Biology, 2018 Transposase-Accessible Chromatin followed by sequencing (ATAC-seq) is a simple protocol for detection of open chromatin. Computational footprinting, the search for regions with depletion of cleavage events due to transcription factor binding, is poorly ...
Zhijian Li +5 more
semanticscholar +1 more source
Pea3 transcription factor promotes neurite outgrowth
Frontiers in Molecular Neuroscience, 2014 Pea3 subfamily of ETS transcription factors consist of three major proteins, Pea3, ERM and ER81. Although important for many different tissues that exhibit branching morphogenesis, the function of Pea3 family in nervous system development and ...
BASAK eKANDEMIR +8 more
doaj +1 more source
Skeletal Muscle, 2021 Background The signal transducer and activator of transcription 6 (STAT6) transcription factor plays a vitally important role in immune cells, where it is activated mainly by interleukin-4 (IL-4).
Mitsutoshi Kurosaka +4 more
doaj +1 more source
Temperature-sensitive protein–DNA dimerizers [PDF]
, 2005 Programmable DNA-binding polyamides coupled to short peptides have led to the creation of synthetic artificial transcription factors. A hairpin polyamide-YPWM tetrapeptide conjugate facilitates the binding of a natural transcription factor Exd to an ...
Ansari, Aseem Z. +6 more
core +1 more source
Nucleic Acids Res., 2017 We present a major update of the HOCOMOCO collection that consists of patterns describing DNA binding specificities for human and mouse transcription factors.
I. Kulakovskiy +11 more
semanticscholar +1 more source
Transcriptional regulation of haematopoietic transcription factors [PDF]
Stem Cell Research & Therapy, 2011 The control of differential gene expression is central to all metazoan biology. Haematopoiesis represents one of the best understood developmental systems where multipotent blood stem cells give rise to a range of phenotypically distinct mature cell types, all characterised by their own distinctive gene expression profiles.
Berthold Göttgens +3 more
openaire +2 more sources