Results 51 to 60 of about 2,521,760 (295)
Transcription Factor Networks in Drosophila melanogaster
Cell Reports, 2014 Specific cellular fates and functions depend on differential gene expression, which occurs primarily at the transcriptional level and is controlled by complex regulatory networks of transcription factors (TFs).
David Y. Rhee +12 more
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Dynamics of gene expression and the regulatory inference problem
, 2008 From the response to external stimuli to cell division and death, the dynamics of living cells is based on the expression of specific genes at specific times.
+10 more
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The Sox2 transcription factor binds RNA
Nature Communications, 2020 Some transcription factors have been proposed to functionally interact with RNA to facilitate proper regulation of gene expression. Here the authors demonstrate that human Sox2 interact directly and with high affinity to RNAs through its HMG DNA-binding ...
Zachariah E. Holmes +6 more
doaj +1 more source
Skeletal Muscle, 2021 Background The signal transducer and activator of transcription 6 (STAT6) transcription factor plays a vitally important role in immune cells, where it is activated mainly by interleukin-4 (IL-4).
Mitsutoshi Kurosaka +4 more
doaj +1 more source
Chlorophyllase is transcriptionally regulated by CsMYB308/CsDOF3 in young leaves of tea plant
Horticultural Plant Journal, 2023 Chlorophyll contributes to tea coloration, which is an important factor in tea quality. Chlorophyll metabolism is induced by light, but the transcriptional regulation responsible for light-induced chlorophyll metabolism is largely unknown in tea leaves ...
Weimin Liu +7 more
doaj +1 more source
Dissection of a complex transcriptional response using genome‐wide transcriptional modelling
Molecular Systems Biology, 2009 Modern genomics technologies generate huge data sets creating a demand for systems level, experimentally verified, analysis techniques. We examined the transcriptional response to DNA damage in a human T cell line (MOLT4) using microarrays.
Martino Barenco +6 more
doaj +1 more source
Pea3 transcription factor promotes neurite outgrowth
Frontiers in Molecular Neuroscience, 2014 Pea3 subfamily of ETS transcription factors consist of three major proteins, Pea3, ERM and ER81. Although important for many different tissues that exhibit branching morphogenesis, the function of Pea3 family in nervous system development and ...
BASAK eKANDEMIR +8 more
doaj +1 more source
Transcription factor p73 regulates Th1 differentiation
Nature Communications, 2020 Heterogeneous helper T (Th) cell responses contribute to differential susceptibility to immunological disorders. Here the authors perform haplotype-based computational screens of 16 inbred mouse strains to identify a transcription factor, p73, as an ...
Min Ren +11 more
doaj +1 more source
Molecular Oncology, 2023 Transcription factors (TFs) are key players in the regulation of gene transcription in mammalian cells. Although high‐throughput screening can be used to identify differentially expressed genes between comparable groups, the precision of the ...
Fanchen Wang +7 more
doaj +1 more source
Genome-wide discovery of modulators of transcriptional interactions in human B lymphocytes
, 2006 Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription factor and its target(s). These include, among others, transcription factor activation
Banerjee, Nilanjana +4 more
core +1 more source