Results 191 to 200 of about 36,472 (203)
Some of the next articles are maybe not open access.
Human Immunology, 2012
Poly(ADP-ribosyl)ation, like acetylation, methylation and phosphorylation, is one of the essential post-translational protein modifications. Poly(ADP-ribose) polymerase 1 (PARP-1), the best characterized member of the PARP family, catalyzes PAR formation, and has been implemented in the in vivo and in vitro inflammatory disease models.
Linlin, Liu +7 more
openaire +2 more sources
Poly(ADP-ribosyl)ation, like acetylation, methylation and phosphorylation, is one of the essential post-translational protein modifications. Poly(ADP-ribose) polymerase 1 (PARP-1), the best characterized member of the PARP family, catalyzes PAR formation, and has been implemented in the in vivo and in vitro inflammatory disease models.
Linlin, Liu +7 more
openaire +2 more sources
Clinical cancer research : an official journal of the American Association for Cancer Research, 1999
Pancreatic adenocarcinoma is a leading cause of adult cancer mortality in the United States. Recent studies have revealed that point mutation of the K-ras oncogene is a common event in pancreatic cancer, and oncogenesis mediated by Ras may also involve activation of Rel/nuclear factor (NF)-kappa B transcription factors. Furthermore, the c-rel member of
W, Wang +5 more
openaire +1 more source
Pancreatic adenocarcinoma is a leading cause of adult cancer mortality in the United States. Recent studies have revealed that point mutation of the K-ras oncogene is a common event in pancreatic cancer, and oncogenesis mediated by Ras may also involve activation of Rel/nuclear factor (NF)-kappa B transcription factors. Furthermore, the c-rel member of
W, Wang +5 more
openaire +1 more source
Clinical cancer research : an official journal of the American Association for Cancer Research, 2002
Activation of transcription factor nuclear factor-kappaB (NF-kappaB) has been shown to play a role in cell proliferation, apoptosis, cytokine production, and oncogenesis. The purpose of this study was to determine whether NF-kappaB is constitutively activated in human gastric carcinoma tissues and, if so, to determine any correlation between NF-kappaB ...
N, Sasaki +10 more
openaire +1 more source
Activation of transcription factor nuclear factor-kappaB (NF-kappaB) has been shown to play a role in cell proliferation, apoptosis, cytokine production, and oncogenesis. The purpose of this study was to determine whether NF-kappaB is constitutively activated in human gastric carcinoma tissues and, if so, to determine any correlation between NF-kappaB ...
N, Sasaki +10 more
openaire +1 more source
Tsitologiia, 1999
DNA binding activity and intracellular distribution of transcription factor NF-kappa B in primary embryo fibroblast (REF) cells transformed by the complementing oncogenes E1A plus cHa-ras have been studied. By means of a gel retardation assay with a regulatory element kappa B, we showed that DNA binding activity of NF-kappa B increased upon ...
Z A, Darieva +2 more
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DNA binding activity and intracellular distribution of transcription factor NF-kappa B in primary embryo fibroblast (REF) cells transformed by the complementing oncogenes E1A plus cHa-ras have been studied. By means of a gel retardation assay with a regulatory element kappa B, we showed that DNA binding activity of NF-kappa B increased upon ...
Z A, Darieva +2 more
openaire +2 more sources
Pediatric Research, 1996
In previous studies, we have shown that RSV replication in A549 cells (a type II alveolar epithelial cell line) induces a dose- and time-dependent release of IL-8. We have subsequently investigated the mechanisms of IL-8 induction. By RT-PCR, the IL-8 mRNA, barely detectable in control cells, was strongly induced by RSV infection; the IL-8 mRNA ...
Roberto Garofalo +7 more
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In previous studies, we have shown that RSV replication in A549 cells (a type II alveolar epithelial cell line) induces a dose- and time-dependent release of IL-8. We have subsequently investigated the mechanisms of IL-8 induction. By RT-PCR, the IL-8 mRNA, barely detectable in control cells, was strongly induced by RSV infection; the IL-8 mRNA ...
Roberto Garofalo +7 more
openaire +1 more source
Abstract The protein interactome of p65 / RELA, the most active subunit of the transcription factor (TF) NF-κB, has not been previously determined in living cells. Using p65-miniTurbo fusion proteins, we identified by biotin tagging > 350 RELA interactors from untreated and IL-1α-stimulated cells, including many TFs (47 % of all ...
Lisa Leib +12 more
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Lisa Leib +12 more
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Essential role of RelA Ser311 phosphorylation by PKC in NF- B transcriptional activation
EMBO Journal, 2003Jorge Moscat +2 more
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