Results 1 to 10 of about 125,603 (234)

Case report: Novel variants in RELA associated with familial Behcet’s-like disease

open access: yesFrontiers in Immunology, 2023
RELA haploinsufficiency is a recently described autoinflammatory condition presenting with intermittent fevers and mucocutaneous ulcerations. The RELA gene encodes the p65 protein, one of five NF-κB family transcription factors.
John F Bohnsack, Kästner Daniel L
exaly   +3 more sources

Aggressive Variant of Hepatic Epstein–Barr Virus-Associated Inflammatory Pseudotumor-like Follicular Dendritic Cell Sarcoma with PD-L1 and SSTR2a Expression

open access: yesDiagnostics, 2023
An aggressive Epstein–Barr virus (EBV)-associated inflammatory pseudotumor-like follicular dendritic cell (IPT-like FDC) sarcoma is reported in an adult female.
Madhur Pardasani   +4 more
doaj   +1 more source

Ependymoma, RELA fusion-positive

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2017
DOI: 10.3969/j.issn.1672-6731.2017.04 ...
Xiao-ling YAN
doaj   +1 more source

COVID-19 Associated Acute Necrotizing Pancreatitis with Normal Serum Amylase and Lipase Levels: Report of an Unusual Finding

open access: yesOman Medical Journal, 2021
Coronaviruses are a large family of single-stranded RNA viruses infecting humans and animals, causing a multitude of symptoms. COVID-19 is not only known to affect the respiratory system, but shows unusual gastrointestinal complications. Pancreatitis can
Hemanth Sudarsanam   +5 more
doaj   +1 more source

Detection of Spinal Tuberculosis by F-18 FDG PET/CT as a Cause of Unusual Referred Pain in the Right Upper Quadrant of Abdomen

open access: yesWorld Journal of Nuclear Medicine, 2022
Tuberculous involvement of the spine (tuberculosis [TB] spine) can cause severe morbidity unless detected and treated early. Apart from the constitutional symptoms, it can present with back pain, kyphosis, gait abnormality, and paraplegia secondary to ...
Santhosh Sampath   +3 more
doaj   +1 more source

Reprogramming RelA [PDF]

open access: yesCell Cycle, 2004
The diversity of activators and targets of the NF-kappaB transcription factor family demands that there be regulatory mechanisms in place to control the specificity with which genes under their control are induced. In part this can be achieved through selective induction of different NF-kappaB subunits and through co-operative interactions with ...
Kirsteen J, Campbell, Neil D, Perkins
openaire   +2 more sources

NF-κB RelA Phosphorylation Regulates RelA Acetylation [PDF]

open access: yesMolecular and Cellular Biology, 2005
The nuclear functions of NF-kappaB p50/RelA heterodimers are regulated in part by posttranslational modifications of its RelA subunit, including phosphorylation and acetylation. Acetylation at lysines 218, 221, and 310 differentially regulates RelA's DNA binding activity, assembly with IkappaBalpha, and transcriptional activity.
Lin-Feng, Chen   +6 more
openaire   +2 more sources

Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1)

open access: yesRenal Failure, 2022
Objective To explore the effect of resveratrol in premature senescence and reveal its anti-premature senescence mechanisms through network pharmacology.
Shuangjun He   +6 more
doaj   +1 more source

A missense variant in NCF1 is associated with susceptibility to unexplained recurrent spontaneous abortion

open access: yesOpen Life Sciences, 2022
Unexplained recurrent spontaneous abortion (URSA) is a major concern in reproductive medicine. Neutrophil cytosolic factor 1 (NCF1) polymorphisms leading to low production of reactive oxygen species (ROS) are strongly associated with autoimmune diseases.
Du Mengxuan   +9 more
doaj   +1 more source

Update on the Pathology of Pediatric Liver Tumors: A Pictorial Review

open access: yesDiagnostics, 2023
Liver tumors in children are uncommon and show remarkable morphologic heterogeneity. Pediatric tumors may arise from either the epithelial or mesenchymal component of the liver and rarely may also show both lines of differentiation.
Priyanka Bhagat   +8 more
doaj   +1 more source

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