Results 1 to 10 of about 123,555 (167)

Case report: Novel variants in RELA associated with familial Behcet’s-like disease

Frontiers in Immunology, 2023
RELA haploinsufficiency is a recently described autoinflammatory condition presenting with intermittent fevers and mucocutaneous ulcerations. The RELA gene encodes the p65 protein, one of five NF-κB family transcription factors.
Fatma Dedeoglu, John Bohnsack, Dedeoglu Fatma   +2 more
exaly   +3 more sources

Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA

Frontiers in Microbiology, 2019
Amino acid starvation in Escherichia coli activates the enzymatic activity of the stringent factor RelA, leading to accumulation of the alarmone nucleotide (p)ppGpp.
Kathryn Jane Turnbull, Ievgen Dzhygyr, Vasili Hauryliuk   +2 more
exaly   +3 more sources

Aggressive Variant of Hepatic Epstein–Barr Virus-Associated Inflammatory Pseudotumor-like Follicular Dendritic Cell Sarcoma with PD-L1 and SSTR2a Expression

Diagnostics, 2023
An aggressive Epstein–Barr virus (EBV)-associated inflammatory pseudotumor-like follicular dendritic cell (IPT-like FDC) sarcoma is reported in an adult female.
Madhur Pardasani, Muthukumarassamy Rajakannu, Mukul Vij, Rajesh Rajalingam, Mohamed Rela   +4 more
doaj   +1 more source

Ependymoma, RELA fusion-positive

Chinese Journal of Contemporary Neurology and Neurosurgery, 2017
DOI: 10.3969/j.issn.1672-6731.2017.04 ...
Xiao-ling YAN
doaj   +1 more source

COVID-19 Associated Acute Necrotizing Pancreatitis with Normal Serum Amylase and Lipase Levels: Report of an Unusual Finding

Oman Medical Journal, 2021
Coronaviruses are a large family of single-stranded RNA viruses infecting humans and animals, causing a multitude of symptoms. COVID-19 is not only known to affect the respiratory system, but shows unusual gastrointestinal complications. Pancreatitis can
Hemanth Sudarsanam, Dillibabu Ethiraj, Navaneetha Kumar Govarthanan, Srinivasan Kalyanasundaram, Sathya Arunachalam Chitra, Saisurendar Mohan   +5 more
doaj   +1 more source

Detection of Spinal Tuberculosis by F-18 FDG PET/CT as a Cause of Unusual Referred Pain in the Right Upper Quadrant of Abdomen

World Journal of Nuclear Medicine, 2022
Tuberculous involvement of the spine (tuberculosis [TB] spine) can cause severe morbidity unless detected and treated early. Apart from the constitutional symptoms, it can present with back pain, kyphosis, gait abnormality, and paraplegia secondary to ...
Santhosh Sampath, Pandurangan Basumani, Anand Kothandaraman, Ravi Ramakrishnan   +3 more
doaj   +1 more source

Reprogramming RelA [PDF]

Cell Cycle, 2004
The diversity of activators and targets of the NF-kappaB transcription factor family demands that there be regulatory mechanisms in place to control the specificity with which genes under their control are induced. In part this can be achieved through selective induction of different NF-kappaB subunits and through co-operative interactions with ...
Kirsteen J, Campbell, Neil D, Perkins
openaire   +2 more sources

NF-κB RelA Phosphorylation Regulates RelA Acetylation [PDF]

Molecular and Cellular Biology, 2005
The nuclear functions of NF-kappaB p50/RelA heterodimers are regulated in part by posttranslational modifications of its RelA subunit, including phosphorylation and acetylation. Acetylation at lysines 218, 221, and 310 differentially regulates RelA's DNA binding activity, assembly with IkappaBalpha, and transcriptional activity.
Lin-Feng, Chen, Samuel A, Williams, Yajun, Mu, Hiroyasu, Nakano, James M, Duerr, Leonard, Buckbinder, Warner C, Greene   +6 more
openaire   +2 more sources

Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1)

Renal Failure, 2022
Objective To explore the effect of resveratrol in premature senescence and reveal its anti-premature senescence mechanisms through network pharmacology.
Shuangjun He, Meng Zhou, Hongming Zheng, Yaowei Wang, Shuhua Wu, Yuan Gao, Jianhong Chen   +6 more
doaj   +1 more source

Dynamic phosphorylation of RelA on Ser42 and Ser45 in response to TNFα stimulation regulates DNA binding and transcription [PDF]

Open Biology, 2016
The NF-κB signalling module controls transcription through a network of protein kinases such as the IKKs, as well as inhibitory proteins (IκBs) and transcription factors including RelA/p65.
Francesco Lanucara, Connie Lam, Jelena Mann, Tom P. Monie, Stefano A. P. Colombo, Stephen W. Holman, James Boyd, Manohar C. Dange, Derek A. Mann, Michael R. H. White, Claire E. Eyers   +10 more
doaj   +1 more source