Results 11 to 20 of about 153,606 (275)
Durante el desarrollo de este proyecto final de carrera se aborda la creación e implementación del protocolo ReLA bajo un lenguaje de programación concreto y unificado en un único ejecutable.
González Rosado, Santiago
core +3 more sources
The molecular mechanisms responsible for opposing oncogenic and tumor-suppressor activities of NF-kB are obscure. Semi-quantitative immunohistochemistry of primary breast tumors using antibodies to RelA, the pleiotropic NF-kB factor, and Ki67 revealed a ...
Bose S. Kochupurakkal, J. Dirk Iglehart
doaj +2 more sources
Update on the Pathology of Pediatric Liver Tumors: A Pictorial Review
Liver tumors in children are uncommon and show remarkable morphologic heterogeneity. Pediatric tumors may arise from either the epithelial or mesenchymal component of the liver and rarely may also show both lines of differentiation.
Priyanka Bhagat +8 more
doaj +1 more source
Unexplained recurrent spontaneous abortion (URSA) is a major concern in reproductive medicine. Neutrophil cytosolic factor 1 (NCF1) polymorphisms leading to low production of reactive oxygen species (ROS) are strongly associated with autoimmune diseases.
Du Mengxuan +9 more
doaj +1 more source
Stapling proteins in the RELA complex inhibits TNFα-induced nuclear translocation of RELA
Discovery of a spirocyclic dimer (SpiD7) that covalently modifies RELA to generate stable high molecular weight complexes. SpiD7 inhibits TNFα-induced nuclear translocation of RELA resulting in the blockade of NF-kB gene transcription, through a previously unexplored modality.
Smit Kour +8 more
openaire +3 more sources
Signaling molecules such as indole (product of tryptophan catabolism) and (p)ppGpp (stringent response regulator) are involved in regulation of physiological processes in bacterial cells aimed to adapt to antibiotics and stresses.
N. M. Kashevarova +3 more
doaj +1 more source
Mycotic pseudoaneurysm (MPA) is a blind, saccular outpouching of the arterial lumen of infective origin. MPA is a rare life-threatening condition and if not treated early, has a 67% mortality rate due to sepsis and hemorrhage.
Sinduja Sivaramalingam +5 more
doaj +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source
COVID-19: Poor outcomes in patients with zinc deficiency
Background: Zinc is a trace element with potent immunoregulatory and antiviral properties, and is utilized in the treatment of coronavirus disease 2019 (COVID-19).
Dinesh Jothimani +10 more
doaj +1 more source
Purification and crystallization of RelA Mutants
The bacterial stringent response is the mechanism that bacteria have to respond to stress conditions such as limiting amino acids, limiting phosphate or fatty acids, carbon limitation or heat shock. When this happens, the stringent response is activated by the small alarmone (p)ppGpp.
Amagat Molas, Jordi
openaire +2 more sources

