Results 21 to 30 of about 125,603 (234)
NF-κB signaling and crosstalk during carcinogenesis
4 open, 2019 Transcription factors (TFs) are proteins that control the transcription of genetic information from DNA to mRNA by binding to specific DNA sequences either on their own or with other proteins as a complex.
Brücher Björn L.D.M. +2 more
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, 2022 Se desarrolla una alternativa mediante la cual los jóvenes puedan aprender sobre el café colombiano, dando a conocer las diferentes variables del producto y sus preparaciones, por medio de herramientas para explorar los sabores del café. ; An alternative is developed through which young people can learn about Colombian coffee, making known the ...
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RelA: a tale of a stitch in time [PDF]
Journal of Clinical Investigation, 2016 Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer in which NF-κB pathways promote biological aggressiveness. In this issue of the JCI, Lesina et al. investigated the role of RelA, the p65 partner of p50 that together form the most common NF-κB complex, in the early stages of pancreatic malignant transformation and in established PDAC.
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Report of the First Training the Colonoscopy Trainers Courses Held in India
Journal of Digestive Endoscopy, 2020 Background and Aim Training the colonoscopy trainers (TCT) courses have become widespread in the United Kingdom and elsewhere but have never taken place in India.
Pandurangan Basumani +4 more
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RELA mRNA Expression in Epithelial Ovarian Cancer: Correlation with rs11820062 Gene Variant
Indonesian Journal of Obstetrics and Gynecology, 2023 and its correlation to i mRNA expression in low-grade and high-grade EOC’s patients from Dr. Cipto Mangunkusumo General hospital, Indonesia. Methods: This study is cross-sectional with a total of 65 healthy subjects and 80 ovarian biopsies (15 ovarian ...
Benedikta D. Saraswati +6 more
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RelA Life and Death Decisions [PDF]
Molecular Cell, 2004 RelA is generally regarded as an activator of prosurvival gene transcription. However, in this issue of Molecular Cell, demonstrate that anticancer drugs turn RelA into an accomplice of apoptosis by instructing it to dominantly repress survival gene transcription.
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Dissection of the Mechanism for the Stringent Factor RelA [PDF]
Molecular Cell, 2002 During conditions of nutrient deprivation, ribosomes are blocked by uncharged tRNA at the A site. The stringent factor RelA binds to blocked ribosomes and catalyzes synthesis of (p)ppGpp, a secondary messenger that induces the stringent response. We demonstrate that binding of RelA and (p)ppGpp synthesis are inversely coupled, i.e., (p)ppGpp synthesis ...
Wendrich, T. +4 more
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EnABLing Cathepsin-Driven Melanoma Metastasis
Molecular & Cellular Oncology, 2018 Metastatic melanoma remains incurable for many due to its aggressive nature. Secreted cathepsins promote metastasis by cleaving matrix and activating pro-invasive proteases.
Rakshamani Tripathi, Rina Plattner
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Acta Neuropathologica Communications, 2021 Recurrent C11orf95-RELA fusions (RELA FUS ) are the hallmark of supratentorial ependymomas. The presence of RELA as the fusion partner indicates a close association of aberrant NF-κB activity with tumorigenesis.
Tatsuya Ozawa +9 more
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Characterization of RelA inAcinetobacter baumannii
Journal of Bacteriology, 2020 ABSTRACTIn response to nutrient depletion, the RelA and SpoT proteins generate the signaling molecule (p)ppGpp, which then controls a number of downstream effectors to modulate cell physiology. InAcinetobacter baumanniistrain AB5075, arelAortholog (ABUW_3302) was identified by a transposon insertion that conferred an unusual colony phenotype.
María, Pérez-Varela +4 more
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