Results 171 to 180 of about 1,348,561 (316)

Advances in the molecular mechanisms of zinc-finger transcription factors in neurodevelopmental disorders. [PDF]

IBRO Neurosci Rep
Wang H, Yang Y, Ni Z, Qiao X, Guo Y, Wang X, Cao D, Wang Y, Ruan C.   +8 more
europepmc   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

The Expression Level of SOX Family Transcription Factors' mRNA as a Diagnostic Marker for Osteoarthritis. [PDF]

J Clin Med
Baran K, Brzeziańska-Lasota E, Kryczka J, Boncela J, Czechowska A, Kopacz K, Padula G, Nowak K, Domżalski M.   +8 more
europepmc   +1 more source

Transforming growth factor-beta increases transcription of the genes encoding the epidermal growth factor receptor and fibronectin in normal rat kidney fibroblasts.

, 1988
Karol L. Thompson, Richard K. Assoian, Marsha Rich Rosner   +2 more
openalex   +1 more source

Factors Modulating Transcription and Translation in vitro of Ribosomal Protein S20 and Isoleucyl‐tRNA Synthetase from Escherichia coli [PDF]

, 1981
Reinhard Wirth, Veronika KOHLES, August Böck   +2 more
openalex   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Evolution of HD-ZIP transcription factors and their function in cabbage leafy head formation. [PDF]

Front Plant Sci
Zhang J, Chen C, Yang Q, Xu J, Han Z, Ma W, Zhang X, Xu K, Zhao J, Chen X.   +9 more
europepmc   +1 more source

Factors responsible for the higher transcriptional activity of extracts of adenovirus-infected cells fractionate with the TATA box transcription factor.

, 1988
Kelsey Leong, Lydie Brunet, Arnold Berk
openalex   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

Control of ciliary transcriptional programs during spermatogenesis by antagonistic transcription factors. [PDF]

Elife
Wang W, Xing J, Zhang X, Liu H, Liu X, Jiang H, Xu C, Zhao X, Hu Z.   +8 more
europepmc   +1 more source