Results 261 to 270 of about 1,348,561 (316)

Extensive binding of uncharacterized human transcription factors to genomic dark matter

Razavi R, Fathi A, Yellan I, Brechalov A, Laverty KU, Jolma A, Hernandez-Corchado A, Zheng H, Yang AW, Albu M, Barazandeh M, Hu C, Vorontsov IE, Patel ZM, The Codebook Consortium, Kulakovskiy IV, Bucher P, Morris Q, Najafabadi HS, Hughes TR.   +19 more
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Identification of methylation-sensitive human transcription factors using meSMiLE-seq

Gralak AJ, Faltejskova K, Yang AW, Steiner C, Russeil J, Grenningloh N, Inukai S, Demir M, Dainese R, Owen C, Pankevich E, Codebook/GRECO-BIT Consortium, Hughes TR, Kulakovskiy IV, Kribelbauer-Swietek JF, van Mierlo G, Deplancke B.   +16 more
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Evolutionarily recent transcription factors partake in human cell cycle regulation

Pulver C, Forey R, Lederer AR, Begnis M, Rosspopoff O, Carlevaro-Fita J, Martins F, Planet E, Duc J, Raclot C, Offner S, Coudray A, Dorschel A, Trono D.   +13 more
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Transcription factor is not just a transcription factor

Trends in Plant Science, 2022
Plant transcription factors (TFs) play important roles in diverse biological processes, including immunity. A recent study by Zhang et al. reported that the rice TF APIP5 regulates immunity through its roles on transcription and mRNA turnover, advancing our conceptual understanding that plant TF may not only function as a TF.
Li Song, Weitao Li, Xuewei Chen
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Transcription factors

Best Practice & Research Clinical Rheumatology, 2001
The regulation of gene expression by transcription factors is fundamental to the phenotype of all cells. The activated phenotype of cells engaged in inflammatory processes is characterized by induced expression of a diverse set of genes, including cytokines, enzymes and cell adhesion molecules.
M L, Handel, L, Girgis
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Transcription Factors

2022
Transcription factors (TFs) are a large family of regulatory proteins that can increase or decrease the transcription of a particular gene from deoxyribonucleic acid into the corresponding ribonucleic acid. The modular structure of TFs and the presence of distinct interacting domains determine the ability of these factors to associate with each other ...
Caramori G., Nucera F., Coppolino I., Bello F. L., Ruggeri P., Ito K., Di Stefano A., Adcock I. M.   +7 more
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Transcription factor RUNX1

Molecular Biology, 2012
Transcription factor RUNX1 is one of the key regulatory proteins in vertebrates. It controls hematopoiesis and angiogenesis. It is indispensable during embryogenesis for the emergence of sites of definitive hematopoiesis and later in mature organisms for bone marrow blood stem cells differentiation.
Sergey V. Razin, N. V. Petrova, Omar L. Kantidze, E. N. Markova   +3 more
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Transcription factors in autoimmunity

Current Opinion in Immunology, 2003
The identification of two transcription factors that, when mutated, are responsible for severe autoimmune disease in humans is leading to a better understanding of the fundamental processes involved in T-cell tolerance. Both AIRE and FOXP3, identified initially via their association with genetically manipulated mice, are critically involved in ...
Steven F. Ziegler, Fred Ramsdell
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Transcription factor complexes

Current Opinion in Structural Biology, 2002
Considerable progress has been made during the past year on structural studies of the eukaryotic and bacterial transcription factors that control RNA polymerase function via the formation of multiprotein complexes on promoter DNA. Recently determined structures include negative cofactor 2 recognizing a preformed TATA-box-binding protein-DNA binary ...
Stephen K. Burley, Katsuhiko Kamada
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Transcription Factors and Hypopituitarism

Trends in Endocrinology & Metabolism, 1999
Several homeodomain factors are found in the developing anterior pituitary lobe. The production of these developmental transcription factors has distinct temporal and spatial patterns. By interacting with each other, as well as with other extrinsic and intrinsic signals, they control cell determination and specification.
Sally Radovick, Laurie E. Cohen, Fredric E. Wondisford   +2 more
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