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Transcription factors: An overview
The International Journal of Biochemistry & Cell Biology, 1997This special issue of the International Journal of Biochemistry and Cell Biology contains a series of review articles and original papers dealing with the topic of transcription factors. The purpose of this introductory article is to provide an overview of these factors, their mechanism of action, their regulation and the manner in which alterations in
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Transcription factors and osteoblasts
Frontiers in Bioscience, 1998Transcription factors play a key role in determination of the fate of the cells in osteoblastic and chondrocytic lineage. A runt family member, Cbfa, is indispensable for osteoblastic differentiation. Sox 9 and scleraxis are involved in the phenotypic expression in chondrocytes and the cells of early stage connective tissues.
M, Noda +7 more
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Transcription factors on the move
Current Opinion in Plant Biology, 2012Mobile transcription factors play essential roles in plant development including the control of cell identity and tissue patterning, as well as organ initiation and the induction of major developmental switches. Within the past few years, the molecules and cellular structures that regulate the movement of these signals have emerged.
Kimberly L. Gallagher, Shuang Wu
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2002
Publisher Summary Asthma and chronic obstructive pulmonary disease (COPD) are characterized by an increased expression of the components of the inflammatory cascade. Inflammation is the central feature of both the diseases as both involve the recruitment and activation of inflammatory cells and changes in the structural cells of the lung.
Ian M. Adcock, Gaetano Caramori
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Publisher Summary Asthma and chronic obstructive pulmonary disease (COPD) are characterized by an increased expression of the components of the inflammatory cascade. Inflammation is the central feature of both the diseases as both involve the recruitment and activation of inflammatory cells and changes in the structural cells of the lung.
Ian M. Adcock, Gaetano Caramori
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TRANSCRIPTION FACTORS | Overview
2006The term ‘transcription factor’ refers to a large family of proteins, which exert transcriptional control via specific interactions with regulatory gene sequences. Here, we provide a summary of the different classes of the transcription factor divided according to their DNA-binding motifs. The modular structure of transcription factors and the presence
Adcock I. M., Ito K., CARAMORI, Gaetano
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Transcription factors in disease
Current Opinion in Genetics & Development, 1996Mutations affecting several predominantly tissue-specific transcriptional regulators have recently been associated with disease phenotypes. Although the mutational spectrum is variable, many of the reported cases involve clear loss-of-function mutations-such as Waardenburg syndrome type 1, aniridia and Rubinstein-Taybi syndrome-suggesting that the ...
Dieter Engelkamp, Veronica van Heyningen
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Trends in Plant Science, 2010
WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and
Imre E. Somssich +3 more
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WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and
Imre E. Somssich +3 more
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Cytokines and transcription factors
Cytokine, 1990Transcriptional induction is mediated by transcription factors, which influence gene expression by interacting with specific elements in their regulatory regions. Here we discuss transcription factors involved in the regulation of cytokines and their receptors (interleukin-2, interleukin-2 receptor alpha chain, and interferon-beta), as well as ...
Scott K. Durum, Kathrin Muegge
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Eukaryotic transcription factors
Current Opinion in Structural Biology, 1998The structural characterization of eukaryotic transcription factors that interact with DNA has advanced on two fronts in the past two years. New complexes of transcription factors bound to TATA-box DNA include the TFIIA-TBP-DNA complex as well as human and archaeal TBP-DNA and TFIIB-TBP-DNA complexes, respectively.
Song Tan, Timothy J. Richmond
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Plant and Cell Physiology, 1995
Transcriptional regulation of gene expression relies on the recognition of promoter elements by transcription factors. In the past several years, a considerable number of (putative) transcription factors have been identified in plants. Some genes coding for these factors were isolated by south-western screening with oligonucleotides as a probe or by ...
Masaki Iwabuchi, Tetsuo Meshi
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Transcriptional regulation of gene expression relies on the recognition of promoter elements by transcription factors. In the past several years, a considerable number of (putative) transcription factors have been identified in plants. Some genes coding for these factors were isolated by south-western screening with oligonucleotides as a probe or by ...
Masaki Iwabuchi, Tetsuo Meshi
openaire +3 more sources