Results 301 to 310 of about 5,966,093 (336)
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Activating Transcription in Bacteria
Annual Review of Microbiology, 2012Bacteria use a variety of mechanisms to direct RNA polymerase to specific promoters in order to activate transcription in response to growth signals or environmental cues. Activation can be due to factors that interact at specific promoters, thereby increasing transcription directed by these promoters.
David J, Lee +2 more
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Cytokine Activation of Transcription
2006In this review we have attempted to outline the events leading to cytokine-mediated gene transcription by using that Jak/STAT and theNF-kB pathways as two examples. It is important to remember that cytokine activation of gene transcription is not the result of a single, linear signaling cascade, but involves a complex network of interacting signal ...
K A, Mowen, M, David
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Transcription activation by catabolite activator protein (CAP)
Journal of Molecular Biology, 1999Transcription activation by Escherichia coli catabolite activator protein (CAP) at each of two classes of simple CAP-dependent promoters is understood in structural and mechanistic detail. At class I CAP-dependent promoters, CAP activates transcription from a DNA site located upstream of the DNA site for RNA polymerase holoenzyme (RNAP); at these ...
S, Busby, R H, Ebright
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Engineering Vibrio fischeri transcriptional activator LuxR for diverse transcriptional activities
Biotechnology Letters, 2016To alter DNA binding specificity of Vibrio fischeri LuxR and to expand the toolbox for constructing synthetic networks.A mutation library (about 10,000 individuals) of the DNA binding domain of LuxR were generated. A genetic selection was performed to obtain LuxR mutants that recognize three lux box DNA variants that are not recognized by wild-type ...
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A brain-specific transcription activator
Neuron, 1989We have identified a DNA binding protein, named BETA, that interacts with the same (B) transcriptional regulatory sequence as the known transcription factor NF-kappa B. BETA is found only in gray matter throughout the brain, and not in a variety of other rat tissues.
M, Korner +4 more
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The Plant Cell
Abstract Enhancing the transcriptional activation activity of transcription factors (TFs) has multiple applications in organism improvement, metabolic engineering, and other aspects of plant science, but the approaches remain unclear.
Chaochao He +16 more
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Abstract Enhancing the transcriptional activation activity of transcription factors (TFs) has multiple applications in organism improvement, metabolic engineering, and other aspects of plant science, but the approaches remain unclear.
Chaochao He +16 more
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Screening of transcription factors with transcriptional initiation activity
Gene, 2013A majority of mammalian promoters are associated with CpG islands. CpG island promoters frequently lack common core promoter elements, such as the TATA box, and often have dispersed transcription start sites. The mechanism through which CpG island promoters are transcriptionally initiated remains unclear.
Lang, Zhang +4 more
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Redox regulation of transcriptional activators
Free Radical Biology and Medicine, 1996Transcription factors/activators are a group of proteins that bind to specific consensus sequences (cis elements) in the promoter regions of downstream target/effector genes and transactivate or repress effector gene expression. The up- or downregulation of effector genes will ultimately lead to many biological changes such as proliferation, growth ...
Y, Sun, L W, Oberley
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