Unraveling G‐Quadruplex and i‐Motif Coexistence Within a Double‐Stranded DNA
Angewandte Chemie, EarlyView.The relative thermodynamic profiles of G‐quadruplex (G4), i‐Motif (iM), and the duplex counterpart tune the simultaneous G4 and iM formation within a double‐stranded (ds) DNA. ABSTRACT DNA can transiently fold into variable arrangements, which are expected to exploit regulatory functions. Guanine‐rich sequences can fold into G‐quadruplexes (G4s), while
Davide Auricchio +7 more
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Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis
Angewandte Chemie, EarlyView.The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood +6 more
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Integrated Differential Expression Analysis and WGCNA Identify Hub Genes Underlying Cotton Plant Height Development. [PDF]
Int J Mol SciQi R +7 more
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The Mediator Complex: From Transcriptional Regulation to Disease Pathogenesis. [PDF]
Int J Mol SciIyer S, Ito T, Nakagawa T, Hattori N.
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Collective RNAP Dynamics Link Transcriptional Strength to Fidelity. [PDF]
J Phys Chem LettMidha T, Kolomeisky AB, Igoshin OA.
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Oocyte vitrification disrupts zygotic genome activation in embryos by impairing maternal spliceosome translation and Crxos splicing. [PDF]
PLoS GenetQin J +16 more
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MPK3 as a Signalling Hub in Plants: Integrating Plant Growth, Development and Stress Response. [PDF]
Plants (Basel)Gao F +9 more
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Conserved protein Seb1 that interacts with RNA polymerase II and RNA is an antipausing transcription elongation factor. [PDF]
RNAKuś K +3 more
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