Results 231 to 240 of about 4,769,934 (397)

Transcriptional regulation of hepatic lipogenesis

open access: yesNature reviews. Molecular cell biology, 2015
Yuhui Wang   +3 more
semanticscholar   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

The role of ankyrin repeat-containing proteins in epigenetic and transcriptional regulation. [PDF]

open access: yesCell Death Discov
Wu M   +7 more
europepmc   +1 more source

Transcriptional regulation of the tyrosine aminotransferase gene [PDF]

open access: yes, 1989
Boshart, Michael   +6 more
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Genetic transcriptional regulation profiling of cartilage reveals pathogenesis of osteoarthritis. [PDF]

open access: yesEBioMedicine
Tian W   +14 more
europepmc   +1 more source

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

open access: yesNature Cell Biology, 2013
Jaeseok Han   +12 more
semanticscholar   +1 more source

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