Results 71 to 80 of about 4,769,934 (397)
Transcriptional memory emerges from cooperative histone modifications [PDF]
, 2011 Background Transcriptional regulation in cells makes use of diverse mechanisms to ensure that functional states can be maintained and adapted to variable environments; among them are chromatin-related mechanisms.
Hans Binder +4 more
core +1 more source
Diffusion, dimensionality and noise in transcriptional regulation
, 2007 The precision of biochemical signaling is limited by randomness in the diffusive arrival of molecules at their targets. For proteins binding to the specific sites on the DNA and regulating transcription, the ability of the proteins to diffuse in one ...
E. M. Lifshitz +4 more
core +1 more source
Estrogen-related receptor α (ERRα) : a novel target in type 2 diabetes [PDF]
, 2005 Recent studies have shown that reduced mitochondrial content and function in skeletal muscle are common features of type 2 diabetes. Here, we review the molecular mechanisms involved in the regulation of mitochondrial genes in skeletal muscle, focusing ...
Handschin, C., Mootha, V. K.
core +1 more source
Post-Transcriptional Regulation of Anti-Apoptotic BCL2 Family Members
International Journal of Molecular Sciences, 2018 Anti-apoptotic B cell lymphoma 2 (BCL2) family members (BCL2, MCL1, BCLxL, BCLW, and BFL1) are key players in the regulation of intrinsic apoptosis.
J. Cui, W. Placzek
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Transcriptional regulation by STAT6 [PDF]
Immunologic Research, 2011 Signal transducer and activator of transcription (STAT) proteins are critical mediators of cytokine signaling. Among the seven STAT proteins, STAT6 is activated by IL-4 and IL-13 and plays a predominant role in the immune system. However, there is increasing evidence that STAT6 may function in other tissues and organ systems.
Mark H. Kaplan, Shreevrat Goenka
openaire +3 more sources
A Quarter Century History of ATML1 Gene Research
Plants, 2021 The cloning of the ATML1 gene, encoding an HD-ZIP class IV transcription factor, was first reported in 1996. Because ATML1 mRNA was preferentially detected in the shoot epidermis, cis-regulatory sequences of ATML1 have been used to drive gene expression ...
Hiroyuki Iida, Shinobu Takada
doaj +1 more source
ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenes [PDF]
, 2007 ChIP-on-chip has emerged as a powerful tool to dissect the complex network of regulatory interactions between transcription factors and their targets.
A. A. Ferrando +27 more
core +3 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Transcriptional regulation of adipogenesis [PDF]
Genes & Development, 2000 Version of ...
Rosen, Evan D. +3 more
openaire +4 more sources