Results 51 to 60 of about 2,483,359 (253)
Nature Communications, 2017 CD4 and CD8 T cells develop in the thymus with their transcription programs controlled by ThPOK and Runx3, respectively. Here the authors show that a pre-commitment event modulated by the transcription factor, Bcl11b, is required for the proper ...
Satoshi Kojo +18 more
doaj +1 more source
Cells, 2020 PRDI-BF1 (positive regulatory domain I-binding factor 1) and RIZ1 (retinoblastoma protein-interacting zinc finger gene 1) (PR) homologous domain containing (PRDM) transcription factors are expressed in neuronal and stem cell systems, and they exert ...
Paweł Leszczyński +5 more
doaj +1 more source
Transcriptional and Post-Transcriptional Regulation of Autophagy
Cells, 2022 Autophagy is a widely conserved process in eukaryotes that is involved in a series of physiological and pathological events, including development, immunity, neurodegenerative disease, and tumorigenesis.
Qiuqin Ma +5 more
doaj +1 more source
Regulation of HSV Transcription.
Journal of Investigative Dermatology, 1984 Herpes simplex virus (HSV) transcripts share many features with both cellular mRNA and the mRNAs expressed by other nuclear-replicating DNA viruses: they are capped, polyadenylated, and generally have an approximately 150 base leader between the cap and translation initiation codon.
openaire +2 more sources
Post-transcriptional regulation of glucocorticoid function
, 2015 Glucocorticoids (GCs) are corticosteroid hormones critically involved in the homeostatic control of stress and immune responses. Endogenous GCs generally tend to support the innate immune responses while inhibiting overexpressed adaptive immune responses.
Ishmael, Faoud T. +3 more
core +1 more source
Regulation of sporulation in the yeast Saccharomyces cerevisiae. [PDF]
, 2010 Sporulation of the budding yeast Saccharomyces cerevisiae — equivalent to gametogenesis in higher organisms, is a complex differentiation program induced by starvation of cells for nitrogen and carbon.
Rytka, Joanna +5 more
core +2 more sources
R-loops in normal and malignant hematopoiesis
Frontiers in Hematology, 2023 An R-loop is a nucleic acid structure consisting of a DNA : RNA hybrid and single-stranded DNA. It is formed physiologically in normal cells and is involved in transcription, replication, and gene rearrangement; in particular, it has multiple roles ...
Mayumi Hirayama +3 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
The grammar of transcriptional regulation [PDF]
Human Genetics, 2014 Eukaryotes employ combinatorial strategies to generate a variety of expression patterns from a relatively small set of regulatory DNA elements. As in any other language, deciphering the mapping between DNA and expression requires an understanding of the set of rules that govern basic principles in transcriptional regulation, the functional elements ...
Shira Weingarten-Gabbay, Eran Segal
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Evolution of Regulated Transcription [PDF]
Cells, 2020 The genomes of all organisms abound with various cis-regulatory elements, which control gene activity. Transcriptional enhancers are a key group of such elements in eukaryotes and are DNA regions that form physical contacts with gene promoters and precisely orchestrate gene expression programs.
Oleg V. Bylino +2 more
openaire +3 more sources