Reconceptualizing transcriptional slippage in plant RNA viruses [PDF]
mBioRNA viruses have evolved sophisticated strategies to exploit the limited encoded information within their typically compact genomes. One of them, named transcriptional slippage (TS), is characterized by the appearance of indels in nascent viral RNAs ...
Adrian A. Valli +6 more
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Turnip Mosaic Virus Transcriptional Slippage Dynamics and Distribution in RNA Subpopulations [PDF]
Molecular Plant-Microbe Interactions, 2022 Potyviruses comprise the largest and most important group of plant positive-strand RNA viruses. The potyviral cell-to-cell movement protein P3N-PIPO is expressed via transcriptional slippage at a conserved GAAAAAA sequence, leading to insertion of an ...
Kairi Kärblane +2 more
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Evaluation of GFP reporter utility for analysis of transcriptional slippage during gene expression [PDF]
Microbial Cell Factories, 2018 Background Epimutations arising from transcriptional slippage seem to have more important role in regulating gene expression than earlier though. Since the level and the fidelity of transcription primarily determine the overall efficiency of gene ...
Ewa Wons +3 more
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Integrated Proteomics and Transcriptomics Analyses Reveal the Transcriptional Slippage of a Bymovirus P3N-PIPO Gene Expressed from a PVX Vector in Nicotiana benthamiana [PDF]
Viruses, 2021 P3N-PIPO (P3 N-terminal fused with Pretty Interesting Potyviridae ORF), the movement protein of potyviruses, is expressed as a translational fusion with the N-terminus of P3 in potyviruses.
Chulang Yu +9 more
doaj +6 more sources
Firmicutes-enriched IS1447 represents a group of IS3-family insertion sequences exhibiting unique + 1 transcriptional slippage [PDF]
Biotechnology for Biofuels, 2018 Background Bacterial insertion sequences (ISs) are ubiquitous mobile genetic elements that play important roles in genome plasticity, cell adaptability, and function evolution. ISs of various families and subgroups contain significantly diverse molecular
Ya-Jun Liu +5 more
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Transcriptional Slippage and RNA Editing Increase the Diversity of Transcripts in Chloroplasts: Insight from Deep Sequencing of Vigna radiata Genome and Transcriptome. [PDF]
PLoS ONE, 2015 We performed deep sequencing of the nuclear and organellar genomes of three mungbean genotypes: Vigna radiata ssp. sublobata TC1966, V. radiata var. radiata NM92 and the recombinant inbred line RIL59 derived from a cross between TC1966 and NM92. Moreover,
Ching-Ping Lin +5 more
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A diagnostic RNA sequencing assay for direct identification and interpretation of pathogenic variants in the FBN1 gene [PDF]
Frontiers in Molecular BiosciencesIntroductionThe extensive size and multi-exon structure and the tissue-restricted expression of the associated gene FBN1 challenge the genetic diagnosis of Marfan Syndrome (MFS).
Manal Irshaid +14 more
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Frontiers in Microbiology, 2021 Tuberculosis is a world widespread disease, caused by Mycobacterium tuberculosis (M.tb). Although considered an obligate aerobe, this organism can resist life-limiting conditions such as microaerophily mainly due to its set of enzymes responsible for ...
Marcos Gustavo Araujo Schwarz +7 more
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DNA methylation and trinucleotide repeat expansion diseases [PDF]
, 2012 Copyright @ 2012 InTechThis article has been made available through the Brunel Open Access Publishing Fund.This article is made available through the Brunel Open Access Publishing ...
Pook, M
core +2 more sources
Transcriptional frameshifting rescues Citrobacter rodentium Type VI secretion by the production of two length variants from the prematurely interrupted tssM gene [PDF]
, 2013 The Type VI secretion system (T6SS) mediates toxin delivery into both eukaryotic and prokaryotic cells. It is composed of a cytoplasmic structure resembling the tail of contractile bacteriophages anchored to the cell envelope through a membrane complex ...
Atkins, John F. +3 more
core +8 more sources