Polycomb-Focused Transcriptome-Wide Association Study (TWAS) Reveals a Neuronal Identity, Circuit-Maintenance, and Cellular-Logistics Architecture Linking Anorexia Nervosa and Binge-Eating Behaviour. [PDF]
CureusCheung N +4 more
europepmc +1 more source
Revealing the Shared Genetic Architecture of Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Traits Through Genomic Structural Equation Modeling. [PDF]
Genet EpidemiolDong H +5 more
europepmc +1 more source
Identification of immune cell type-specific susceptibility genes in multiple cancers using transcriptome-wide association studies. [PDF]
J Natl Cancer InstQin F +16 more
europepmc +1 more source
When Literature Priors Are Removed: Clinical Rank Shifts and Transancestral Stability in Antipsychotic Low-Density Lipoprotein (LDL)-Risk Modelling. [PDF]
CureusCheung N, Cheung HK, Yu YW, Tsang YY.
europepmc +1 more source
Receptor Contribution Reallocation After Removal of Literature-Derived Weights: A Secondary Sensitivity Analysis of the Integrated Ki-DDD-TWAS Pipeline for Antipsychotic Lipid-Trait Prioritization. [PDF]
CureusCheung N, Cheung HK, Yu YW, Tsang YY.
europepmc +1 more source
Transcriptome-wide Association Studies (TWAS) extend genome-wide association studies (GWAS) by integrating genetically-regulated gene expression models. We performed the most powerful AD-TWAS to date, using summary statistics from -eQTL meta-analyses and
Bush, William S +5 more
core +2 more sources
Multi-omics causal inference of childhood asthma triggered by ambient particulate matter. [PDF]
ERJ Open ResLi H, Ren X, Lei X, Li Y, Dong W.
europepmc +1 more source
Brain multiomic profiling identifies tau-related transcriptomic dysregulation in Alzheimer's disease. [PDF]
Brain CommunOatman SR +19 more
europepmc +1 more source
Leveraging expression quantitative trait loci information in single-cell resolution to identify cell-specific genes for Basal cell carcinoma. [PDF]
PLoS OneDu M, Zhu W, Wang S, Wang R, Li X.
europepmc +1 more source