Results 111 to 120 of about 928,042 (281)
Assessment of the impact of using a reference transcriptome in mapping short RNA-Seq reads. [PDF]
PLoS ONE, 2014 RNA-Seq has become increasingly popular in transcriptome profiling. The major challenge in RNA-Seq data analysis is the accurate mapping of junction reads to their genomic origins.
Shanrong Zhao
doaj +1 more source
A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
bioRxiv, 2018 Genome-, transcriptome- and proteome-wide measurements provide valuable insights into how biological systems are regulated. However, even fundamental aspects relating to which human proteins exist, where they are expressed and in which quantities are not
Dongxue Wang +18 more
semanticscholar +1 more source
The transcriptome of Toxoplasma gondii
BMC Biology, 2005 AbstractBackgroundToxoplasma gondiigives rise to toxoplasmosis, among the most prevalent parasitic diseases of animals and man. Transformation of the tachzyoite stage into the latent bradyzoite-cyst form underlies chronic disease and leads to a lifetime risk of recrudescence in individuals whose immune system becomes compromised.
Michael S. Behnke +5 more
openaire +4 more sources
Nature CommunicationsLong-read RNA sequencing is essential to produce accurate and exhaustive annotation of eukaryotic genomes. Despite advancements in throughput and accuracy, achieving reliable end-to-end identification of RNA transcripts remains a challenge for long-read ...
Sílvia Carbonell-Sala +9 more
doaj +1 more source
BMC Genomics, 2018 Background Without knowledge of their genomic sequences, it is impossible to make functional models of the bacteria that make up human and animal microbiota.
Luis Acuña-Amador +4 more
doaj +1 more source
Transcriptome and genome sequencing uncovers functional variation in humans
Nature, 2013 Genome sequencing projects are discovering millions of genetic variants in humans, and interpretation of their functional effects is essential for understanding the genetic basis of variation in human traits.
T. Lappalainen +56 more
semanticscholar +1 more source
PATTERNA: transcriptome-wide search for functional RNA elements via structural data signatures. [PDF]
, 2018 Establishing a link between RNA structure and function remains a great challenge in RNA biology. The emergence of high-throughput structure profiling experiments is revolutionizing our ability to decipher structure, yet principled approaches for ...
Aviran, Sharon, Ledda, Mirko
core
The Sorghum bicolor reference genome: improved assembly, gene annotations, a transcriptome atlas, and signatures of genome organization. [PDF]
, 2017 Sorghum bicolor is a drought tolerant C4 grass used for the production of grain, forage, sugar, and lignocellulosic biomass and a genetic model for C4 grasses due to its relatively small genome (approximately 800 Mbp), diploid genetics, diverse ...
Amirebrahimi, Mojgan +14 more
core +2 more sources
The complexity of the mammalian transcriptome [PDF]
The Journal of Physiology, 2006 A comprehensive understanding of protein and regulatory networks is strictly dependent on the complete description of the transcriptome of cells. After the determination of the genome sequence of several mammalian species, gene identification is based on in silico predictions followed by evidence of transcription.
Roberto Simone +9 more
openaire +3 more sources
Nanopore native RNA sequencing of a human poly(A) transcriptome
bioRxiv, 2018 High-throughput complementary DNA sequencing technologies have advanced our understanding of transcriptome complexity and regulation. However, these methods lose information contained in biological RNA because the copied reads are often short and ...
R. Workman +21 more
semanticscholar +1 more source