Results 11 to 20 of about 928,042 (281)

Transcriptomics in ecotoxicology [PDF]

open access: yesAnalytical and Bioanalytical Chemistry, 2010
The emergence of analytical tools for high-throughput screening of biomolecules has revolutionized the way in which toxicologists explore the impact of chemicals or other stressors on organisms. One of the most developed and routinely applied high-throughput analysis approaches is transcriptomics, also often referred to as gene expression profiling ...
Danielle J. Madureira   +5 more
openaire   +4 more sources

Pathovar Transcriptomes [PDF]

open access: yesmSystems, 2017
Archetypal pathogenic bacterial strains are often used to elucidate regulatory networks of an entire pathovar, which encompasses multiple lineages and phylogroups. With enteropathogenic Escherichia coli (EPEC) as a model system, Hazen and colleagues (mSystems 6:e00024-17, 2017, https://doi.org/10.1128 ...
Amy Platenkamp, Jay L. Mellies
openaire   +3 more sources

Hot Transcriptomics [PDF]

open access: yesArchaea, 2010
DNA microarray technology allows for a quick and easy comparison of complete transcriptomes, resulting in improved molecular insight in fluctuations of gene expression. After emergence of the microarray technology about a decade ago, the technique has now matured and has become routine in many molecular biology laboratories.
Walther, J.   +2 more
openaire   +3 more sources

Museum of Spatial Transcriptomics [PDF]

open access: yesNature Methods, 2021
AbstractThe function of many biological systems, such as embryos, liver lobules, intestinal villi, and tumors depends on the spatial organization of their cells. In the past decade high-throughput technologies have been developed to quantify gene expression in space, and computational methods have been developed that leverage spatial gene expression ...
Lambda Moses, Lior Pachter
openaire   +6 more sources

RNA Sequencing Reveals Widespread Transcription of Natural Antisense RNAs in Entamoeba Species

open access: yesMicroorganisms, 2022
Entamoeba is a genus of Amoebozoa that includes the intestine-colonizing pathogenic species Entamoeba histolytica. To understand the basis of gene regulation in E.
Damien Mornico   +7 more
doaj   +1 more source

Evidence of neutral transcriptome evolution in plants [PDF]

open access: yes, 2008
The transcriptome of an organism is its set of gene transcripts (mRNAs) at a defined spatial and temporal locus. Because gene expression is affected markedly by environmental and developmental perturbations, it is widely assumed that transcriptome ...
Bailey   +34 more
core   +1 more source

Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring

open access: yesJournal of Fungi, 2021
Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood
François Danion   +11 more
doaj   +1 more source

Tissue resolved, gene structure refined equine transcriptome. [PDF]

open access: yes, 2017
BackgroundTranscriptome interpretation relies on a good-quality reference transcriptome for accurate quantification of gene expression as well as functional analysis of genetic variants.
Bellone, RR   +9 more
core   +1 more source

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

open access: yesJournal of Neuroscience, 2014
The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better understand the functions and interactions of the cell types that comprise these classes, we acutely purified representative ...
Ye Zhang   +16 more
semanticscholar   +1 more source

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