Results 11 to 20 of about 820,451 (317)

Imputed genomes of historical horses provide insights into modern breeding

iScience, 2023
Summary: Historical genomes can provide important insights into recent genomic changes in horses, especially the development of modern breeds. In this study, we characterized 8.7 million genomic variants from a panel of 430 horses from 73 breeds ...
Evelyn T. Todd, Aurore Fromentier, Richard Sutcliffe, Yvette Running Horse Collin, Aude Perdereau, Jean-Marc Aury, Camille Èche, Olivier Bouchez, Cécile Donnadieu, Patrick Wincker, Ted Kalbfleisch, Jessica L. Petersen, Ludovic Orlando   +12 more
doaj   +1 more source

Transcriptomics in ecotoxicology [PDF]

Analytical and Bioanalytical Chemistry, 2010
The emergence of analytical tools for high-throughput screening of biomolecules has revolutionized the way in which toxicologists explore the impact of chemicals or other stressors on organisms. One of the most developed and routinely applied high-throughput analysis approaches is transcriptomics, also often referred to as gene expression profiling ...
Schirmer, Kristin, Fischer, Beat, Madureira, Danielle, Pillai, Smitha   +3 more
openaire   +3 more sources

Long Oligonucleotide Arrays on Nylon for Large-Scale Gene Expression Analysis

BioTechniques, 2002
To date, most studies of multigenic expression patterns by long DNA array have used DNA fragments as probes. These probes are usually obtained as PCR products, and this represents a time-consuming and error-prone approach, requiring strict quality ...
M. El Atifi, I. Dupré, B. Rostaing, E.M. Chambaz, A.L. Benabid, F. Berger   +5 more
doaj   +1 more source

Fruit fly phylogeny imprints bacterial gut microbiota

Evolutionary Applications, 2022
One promising avenue for reconciling the goals of crop production and ecosystem preservation consists in the manipulation of beneficial biotic interactions, such as between insects and microbes.
Virginie Ravigné, Nathalie Becker, François Massol, Erwan Guichoux, Christophe Boury, Frédéric Mahé, Benoit Facon   +6 more
doaj   +1 more source

Tissue resolved, gene structure refined equine transcriptome. [PDF]

, 2017
BackgroundTranscriptome interpretation relies on a good-quality reference transcriptome for accurate quantification of gene expression as well as functional analysis of genetic variants.
Bellone, RR, Brown, CT, Finno, CJ, Mansour, TA, Mienaltowski, MJ, Murray, JD, Penedo, MC, Ross, PJ, Scott, EY, Valberg, SJ   +9 more
core   +1 more source

Induced Pluripotent Stem Cell Generation-Associated Point Mutations Arise during the Initial Stages of the Conversion of These Cells

Stem Cell Reports, 2014
A large number of point mutations have been identified in induced pluripotent stem cell (iPSC) genomes to date. Whether these mutations are associated with iPSC generation is an important and controversial issue.
Mayumi Sugiura, Yasuji Kasama, Ryoko Araki, Yuko Hoki, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando, Masumi Abe   +8 more
doaj   +1 more source

Advancing transcriptome platforms [PDF]

, 2011
During the last decade of years, remarkable technological innovations have emerged that allow the direct or indirect determination of the transcriptome at unprecedented scale and speed.
Shuobo Shi
core   +2 more sources

RNA Sequencing Reveals Widespread Transcription of Natural Antisense RNAs in Entamoeba Species

Microorganisms, 2022
Entamoeba is a genus of Amoebozoa that includes the intestine-colonizing pathogenic species Entamoeba histolytica. To understand the basis of gene regulation in E.
Damien Mornico, Chung-Chau Hon, Mikael Koutero, Christian Weber, Jean-Yves Coppée, C Graham Clark, Marie-Agnes Dillies, Nancy Guillen   +7 more
doaj   +1 more source

Analysis of wheat SAGE tags reveals evidence for widespread antisense transcription [PDF]

, 2008
BACKGROUND: Serial Analysis of Gene Expression (SAGE) is a powerful tool for genome-wide transcription studies. Unlike microarrays, it has the ability to detect novel forms of RNA such as alternatively spliced and antisense transcripts, without the need ...
Barker, Gary L A, Berry, Simon, Biggi, Gaia F, Coghill, Jane, Dunwell, Jim, Edwards, Keith J, Gibbings, George, Poole, Rebecca L, Werner, Kay   +8 more
core   +2 more sources

Transcriptomics in toxicology [PDF]

Food and Chemical Toxicology, 2017
Xenobiotics, of which many are toxic, may enter the human body through multiple routes. Excessive human exposure to xenobiotics may exceed the body's capacity to defend against the xenobiotic-induced toxicity and result in potentially fatal adverse health effects.
openaire   +2 more sources