Results 11 to 20 of about 928,042 (281)
Transcriptomics in ecotoxicology [PDF]
The emergence of analytical tools for high-throughput screening of biomolecules has revolutionized the way in which toxicologists explore the impact of chemicals or other stressors on organisms. One of the most developed and routinely applied high-throughput analysis approaches is transcriptomics, also often referred to as gene expression profiling ...
Danielle J. Madureira+5 more
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Archetypal pathogenic bacterial strains are often used to elucidate regulatory networks of an entire pathovar, which encompasses multiple lineages and phylogroups. With enteropathogenic Escherichia coli (EPEC) as a model system, Hazen and colleagues (mSystems 6:e00024-17, 2017, https://doi.org/10.1128 ...
Amy Platenkamp, Jay L. Mellies
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DNA microarray technology allows for a quick and easy comparison of complete transcriptomes, resulting in improved molecular insight in fluctuations of gene expression. After emergence of the microarray technology about a decade ago, the technique has now matured and has become routine in many molecular biology laboratories.
Walther, J.+2 more
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Museum of Spatial Transcriptomics [PDF]
AbstractThe function of many biological systems, such as embryos, liver lobules, intestinal villi, and tumors depends on the spatial organization of their cells. In the past decade high-throughput technologies have been developed to quantify gene expression in space, and computational methods have been developed that leverage spatial gene expression ...
Lambda Moses, Lior Pachter
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RNA Sequencing Reveals Widespread Transcription of Natural Antisense RNAs in Entamoeba Species
Entamoeba is a genus of Amoebozoa that includes the intestine-colonizing pathogenic species Entamoeba histolytica. To understand the basis of gene regulation in E.
Damien Mornico+7 more
doaj +1 more source
Evidence of neutral transcriptome evolution in plants [PDF]
The transcriptome of an organism is its set of gene transcripts (mRNAs) at a defined spatial and temporal locus. Because gene expression is affected markedly by environmental and developmental perturbations, it is widely assumed that transcriptome ...
Bailey+34 more
core +1 more source
Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring
Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood
François Danion+11 more
doaj +1 more source
Tissue resolved, gene structure refined equine transcriptome. [PDF]
BackgroundTranscriptome interpretation relies on a good-quality reference transcriptome for accurate quantification of gene expression as well as functional analysis of genetic variants.
Bellone, RR+9 more
core +1 more source
The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better understand the functions and interactions of the cell types that comprise these classes, we acutely purified representative ...
Ye Zhang+16 more
semanticscholar +1 more source