Results 11 to 20 of about 450,406 (197)
Transcriptomics in ecotoxicology [PDF]
Analytical and Bioanalytical Chemistry, 2010 The emergence of analytical tools for high-throughput screening of biomolecules has revolutionized the way in which toxicologists explore the impact of chemicals or other stressors on organisms. One of the most developed and routinely applied high-throughput analysis approaches is transcriptomics, also often referred to as gene expression profiling ...
Danielle J. Madureira +5 more
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mSystems, 2017 Archetypal pathogenic bacterial strains are often used to elucidate regulatory networks of an entire pathovar, which encompasses multiple lineages and phylogroups. With enteropathogenic Escherichia coli (EPEC) as a model system, Hazen and colleagues (mSystems 6:e00024-17, 2017, https://doi.org/10.1128 ...
Amy Platenkamp, Jay L. Mellies
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Archaea, 2010 DNA microarray technology allows for a quick and easy comparison of complete transcriptomes, resulting in improved molecular insight in fluctuations of gene expression. After emergence of the microarray technology about a decade ago, the technique has now matured and has become routine in many molecular biology laboratories.
Walther, J. +2 more
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Museum of Spatial Transcriptomics [PDF]
Nature Methods, 2021 AbstractThe function of many biological systems, such as embryos, liver lobules, intestinal villi, and tumors depends on the spatial organization of their cells. In the past decade high-throughput technologies have been developed to quantify gene expression in space, and computational methods have been developed that leverage spatial gene expression ...
Lambda Moses, Lior Pachter
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RNA Sequencing Reveals Widespread Transcription of Natural Antisense RNAs in Entamoeba Species
Microorganisms, 2022 Entamoeba is a genus of Amoebozoa that includes the intestine-colonizing pathogenic species Entamoeba histolytica. To understand the basis of gene regulation in E.
Damien Mornico +7 more
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Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring
Journal of Fungi, 2021 Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood
François Danion +11 more
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Stem Cell Reports, 2014 A large number of point mutations have been identified in induced pluripotent stem cell (iPSC) genomes to date. Whether these mutations are associated with iPSC generation is an important and controversial issue.
Mayumi Sugiura +8 more
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Oomycete transcriptomics database: A resource for oomycete transcriptomes [PDF]
BMC Genomics, 2012 Oomycete pathogens have attracted significant attention in recent years due to their economic impact. With improving sequencing technologies, large amounts of oomycete transcriptomics data are now available which have great biological utility. A known bottleneck with next generation sequencing data however lies with their analysis, interpretation ...
Brett M. Tyler +3 more
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PLOS Computational Biology, 2017 © 2017 Lowe et al. Transcriptomics technologies are the techniques used to study an organism’s transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription.
Rohan Lowe +4 more
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