Results 51 to 60 of about 450,406 (197)

At the dawn of the transcriptomic medicine [PDF]

open access: yesExperimental Biology and Medicine, 2020
Progress in genomic analytical technologies has improved our possibilities to obtain information regarding DNA, RNA, and their dynamic changes that occur over time or in response to specific challenges. This information describes the blueprint for cells, tissues, and organisms and has fundamental importance for all living organisms.
Gea Koks   +4 more
openaire   +4 more sources

A seven-gene cluster in Ruminiclostridium cellulolyticum is essential for signalization, uptake and catabolism of the degradation products of cellulose hydrolysis

open access: yesBiotechnology for Biofuels, 2017
Background Like a number of anaerobic and cellulolytic Gram-positive bacteria, the model microorganism Ruminiclostridium cellulolyticum produces extracellular multi-enzymatic complexes called cellulosomes, which efficiently degrade the crystalline ...
Aurélie Fosses   +8 more
doaj   +1 more source

Fishing Into the MicroRNA Transcriptome [PDF]

open access: yesFrontiers in Genetics, 2018
In the last decade, several studies have been focused on revealing the microRNA (miRNA) repertoire and determining their functions in farm animals such as poultry, pigs, cattle, and fish. These small non-protein coding RNA molecules (18-25 nucleotides) are capable of controlling gene expression by binding to messenger RNA (mRNA) targets, thus ...
Herkenhoff, Marcos E.   +6 more
openaire   +5 more sources

Spatial Transcriptomic Technologies

open access: yesCells, 2023
Spatial transcriptomic technologies enable measurement of expression levels of genes systematically throughout tissue space, deepening our understanding of cellular organizations and interactions within tissues as well as illuminating biological insights in neuroscience, developmental biology and a range of diseases, including cancer.
Tsai-Ying Chen   +3 more
openaire   +3 more sources

Muscle transcriptome analysis reveals molecular pathways and biomarkers involved in extreme ultimate pH and meat defect occurrence in chicken

open access: yesScientific Reports, 2017
The processing ability and sensory quality of chicken breast meat are highly related to its ultimate pH (pHu), which is mainly determined by the amount of glycogen in the muscle at death.
Stéphane Beauclercq   +12 more
doaj   +1 more source

Inside the granulosa transcriptome

open access: yesGynecological Endocrinology, 2016
The somatic component of follicular structure is a mixture of different cell types, represented by Granulosa cells (GCs) that are the paracrine regulators of the oocyte growth. GCs finely support this process by a continuous bidirectional talk with oocyte, which ensure oocyte quality and competence.
D'AURORA, MARCO   +5 more
openaire   +3 more sources

Spatial transcriptomics in neuroscience

open access: yesExperimental & Molecular Medicine, 2023
AbstractThe brain is one of the most complex living tissue types and is composed of an exceptional diversity of cell types displaying unique functional connectivity. Single-cell RNA sequencing (scRNA-seq) can be used to efficiently map the molecular identities of the various cell types in the brain by providing the transcriptomic profiles of individual
Namyoung Jung, Tae-Kyung Kim
openaire   +3 more sources

Evolution: The Plastic Transcriptome [PDF]

open access: yesCurrent Biology, 2006
Studies across a wide range of species point to a surprising degree of plasticity in the transcriptional states that organisms can adopt, suggesting that organisms often respond to environmental challenges through wholesale reprogramming of their gene expression.
openaire   +4 more sources

Genomes and Transcriptomes of Duckweeds [PDF]

open access: yesFrontiers in Chemistry, 2018
Duckweeds (Lemnaceae family) are the smallest flowering plants that adapt to the aquatic environment. They are regarded as the promising sustainable feedstock with the characteristics of high starch storage, fast propagation, and global distribution.
Wenqin Wang   +4 more
openaire   +4 more sources

The human olfactory transcriptome [PDF]

open access: yesBMC Genomics, 2016
Olfaction is a versatile sensory mechanism for detecting thousands of volatile odorants. Although molecular basis of odorant signaling is relatively well understood considerable gaps remain in the complete charting of all relevant gene products. To address this challenge, we applied RNAseq to four well-characterized human olfactory epithelial samples ...
Jayant M. Pinto   +10 more
openaire   +3 more sources

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