Comparative Transcriptome Analysis Reveals the Role of the FST Gene in Goose Muscle Development. [PDF]
Wang C +7 more
europepmc +1 more source
CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan +21 more
wiley +1 more source
Comprehensive Metabolome and Transcriptome Analysis of <i>Populus davidiana</i> and Its Response to Drought Stress. [PDF]
Wang Y +8 more
europepmc +1 more source
RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu +12 more
wiley +1 more source
Comparative transcriptome analysis reveals the complex response mechanisms of soybean leaves and roots to salt stress. [PDF]
Huang W +7 more
europepmc +1 more source
This study investigates the role of M2 macrophage‐derived extracellular vesicles (M2 EVs) in prostate cancer (PCa) metastasis. Mechanistically, M2 EVs horizontally transfer TXNDC5 mRNA to PCa cells, where the molecule induces the mesenchymal‐like state (MLS), enhancing PCa migration and invasion.
Cong Hu +14 more
wiley +1 more source
Transcriptome analysis reveals key immune pathways and metabolites associated with resistance to Verticillium dahliae in GbMBL1.1A-overexpressing cotton. [PDF]
Tan D +6 more
europepmc +1 more source
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Single-cell transcriptome analysis elucidates the microenvironmental interactions between colorectal cancer and sarcopenia. [PDF]
Qiu T, Wang X, Li J, Guan Y, Wen H.
europepmc +1 more source
Integrated of metabolome and transcriptome analysis reveals the effect of artificial light at night on Platanus orientalis L. [PDF]
Lv Z +6 more
europepmc +1 more source

