Results 61 to 70 of about 499,194 (265)

Global Gene-expression Analysis of the Response of Salmonella Enteritidis to Egg White Exposure Reveals Multiple Egg White-imposed Stress Responses

Frontiers in Microbiology, 2017
Chicken egg white protects the embryo from bacterial invaders by presenting an assortment of antagonistic activities that combine together to both kill and inhibit growth. The key features of the egg white anti-bacterial system are iron restriction, high
Florence Baron, Florence Baron, Sylvie Bonnassie, Sylvie Bonnassie, Sylvie Bonnassie, Mariah Alabdeh, Mariah Alabdeh, Marie-Françoise Cochet, Marie-Françoise Cochet, Françoise Nau, Françoise Nau, Catherine Guérin-Dubiard, Catherine Guérin-Dubiard, Michel Gautier, Michel Gautier, Simon C. Andrews, Sophie Jan, Sophie Jan   +17 more
doaj   +1 more source

Integrated Excitatory/Inhibitory Imbalance and Transcriptomic Analysis Reveals the Association between Dysregulated Synaptic Genes and Anesthetic-Induced Cognitive Dysfunction

Cells, 2022
Emerging evidence from human epidemiologic and animal studies has demonstrated that developmental anesthesia neurotoxicity could cause long-term cognitive deficits and behavioral problems. However, the underlying mechanisms remain largely unknown.
Yasheng Yan, Sarah Logan, Xiaojie Liu, Bixuan Chen, Congshan Jiang, Thiago Arzua, Ramani Ramchandran, Qing-song Liu, Xiaowen Bai   +8 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Integrated transcriptomic and metabolomic analyses reveal a novel mechanism of resistance to Colletotrichum fructicola in pear

Journal of Integrative Agriculture
Pear anthracnose, caused by Colletotrichum fructicola, is a devastating disease that seriously affects most pear varieties, compromising their yield and quality. However, effective control of this pathogen is lacking.
Xiaomei Tang, Yue Wang, Yuqing Guo, Luoluo Xie, Wei Song, Ziwen Xiao, Ruichang Yin, Zhe Ye, Xueqiu Sun, Wenming Wang, Lun Liu, Zhenfeng Ye, Zhenghui Gao, Bing Jia   +13 more
doaj   +1 more source

Transcriptomic analysis of Sporisorium reilianum in response to the strigolactone analogue GR24

Phytopathologia Mediterranea, 2012
A suppression subtractive hybridization (SSH) approach was used to generate cDNA libraries representing genes differentially expressed in the haploid cells of the maize head smut pathogen Sporisorium reilianum exposed to GR24, a strigolactone analogue ...
Seyed SABBAGH, Mahta MAZAHERI, Naser PANJEHKEH, Mohammad SALARI   +3 more
doaj   +1 more source

Identification of Transcriptome Biomarkers for Severe COVID-19 with Machine Learning Methods

Biomolecules, 2022
The rapid spread of COVID-19 has become a major concern for people’s lives and health all around the world. COVID-19 patients in various phases and severity require individualized treatment given that different patients may develop different symptoms. We
Xiaohong Li, Xianchao Zhou, Shijian Ding, Lei Chen, Kaiyan Feng, Hao Li, Tao Huang, Yu-Dong Cai   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Exogenous Calcium Alleviates Oxidative Stress Caused by Salt Stress in Peanut Seedling Roots by Regulating the Antioxidant Enzyme System and Flavonoid Biosynthesis

Antioxidants
Soil salinity is one of the adversity stresses plants face, and antioxidant defense mechanisms play an essential role in plant resistance. We investigated the effects of exogenous calcium on the antioxidant defense system in peanut seedling roots that ...
Yan Gao, Xuan Dong, Rongjin Wang, Fei Hao, Hui Zhang, Yongyong Zhang, Guolin Lin   +6 more
doaj   +1 more source

Metabolome and Transcriptome Analyses Provide Insights into Glucosinolate Accumulation in the Novel Vegetable Crop Cardamine violifolia

Agronomy, 2023
Cardamine violifolia, a species belonging to the Brassicaceae family, is a novel vegetable crop that is rich in glucosinolates. However, the specific glucosinolate profiles in this species remain unknown. In the present study, four parts of C. violifolia
Shen Rao, Jue Gong, Haodong Liu, Xiaomeng Liu, Shuiyuan Cheng, Hua Cheng, Xin Cong   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source