Results 221 to 230 of about 398,969 (379)

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Method of the Year: spatially resolved transcriptomics

Nature Methods, 2021
V. Marx
semanticscholar   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

The Use of Transcriptomics to Address Questions in Behaviour: Production of a Suppression Subtractive Hybridisation Library from Dominance Hierarchies of Rainbow Trout

, 2005
Lynne U. Sneddon, Javier Margareto, Andrew R. Cossins   +2 more
openalex   +2 more sources

DeepSAGE—digital transcriptomics with high sensitivity, simple experimental protocol and multiplexing of samples [PDF]

, 2006
Kåre Lehmann Nielsen, Annabeth Laursen Høgh, Jeppe Emmersen   +2 more
openalex   +1 more source

Integrating single-cell and spatial transcriptomics to elucidate intercellular tissue dynamics

Nature reviews genetics, 2021
Sophia K. Longo, M. Guo, A. Ji, P. Khavari   +3 more
semanticscholar   +1 more source

Response to: Clinical Imaging Features of Sporadic and Genetic Frontotemporal Lobar Degeneration TDP‐43 A and B

Annals of Clinical and Translational Neurology, EarlyView.
Sergi Borrego‐Écija, Cèlia Cruz‐Escalera, Agnes Perez‐Millán, Jordi Juncà‐Parellà   +3 more
wiley   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

A Comparison of Transcriptomic and Metabonomic Technologies for Identifying Biomarkers Predictive of Two-Year Rodent Cancer Bioassays [PDF]

, 2006
Russell S. Thomas, Thomas M. O’Connell, Linda Pluta, Russell D. Wolfinger, Longlong Yang, Todd J. Page   +5 more
openalex   +1 more source

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

Nature, 2018
N. Schaum, Jim Karkanias, N. Neff, A. May, S. Quake, T. Wyss-Coray, S. Darmanis, Joshua Batson, O. Botvinnik, Michelle B. Chen, Steven Chen, Foad Green, Robert C. Jones, A. Maynard, L. Penland, A. Pisco, R. Sit, Geoffrey M. Stanley, James T. Webber, F. Zanini, Ankit S. Baghel, Isaac Bakerman, I. Bansal, D. Berdnik, Biter Bilen, D. Brownfield, Corey Cain, Min Cho, Giana Cirolia, Stephanie D. Conley, Aaron Demers, K. Demir, A. Morrée, T. Divita, H. D. Bois, Laughing Bear Torrez Dulgeroff, H. Ebadi, F. H. Espinoza, M. Fish, Qiang Gan, B. George, A. Gillich, Geraldine Genetiano, Xueying Gu, G. Gulati, Y. Hang, Shayan Hosseinzadeh, Albin Huang, Tal Iram, Taichi Isobe, Feather Ives, Kevin S. Kao, G. Karnam, Aaron M. Kershner, B. Kiss, W. Kong, Maya E. Kumar, Jonathan Y. Lam, Davis P. Lee, S. Lee, Guang Li, Qingyun Li, Ling Liu, Annie Lo, Wan-Jin Lu, A. Manjunath, Kaia L. May, O. L. May, Marina Mckay, Ross J. Metzger, Marco Mignardi, D. Min, Ahmad N. Nabhan, K. Ng, Joseph J. Noh, R. Patkar, Weng Chuan Peng, R. Puccinelli, Eric J. Rulifson, Shaheen S. Sikandar, Rahul Sinha, K. Szade, Weilun Tan, C. Tato, Krissie Tellez, K. Travaglini, C. Tropini, Lucas M. Waldburger, L. V. Weele, Michael N. Wosczyna, Jinyi Xiang, Soso Xue, Justin Youngyunpipatkul, Macy E. Zardeneta, Fan Zhang, Lu Zhou, Paola Castro, Derek Croote, J. Derisi, Christin S Kuo, B. Lehallier, P. Nguyen, Serena Y Tan, Bruce Wang, H. Yousef, P. Beachy, Charles K. F. Chan, K. C. Huang, K. Weinberg, Sean M. Wu, B. Barres, M. Clarke, Seung K. Kim, M. Krasnow, R. Nusse, T. Rando, J. Sonnenburg, I. Weissman   +117 more
semanticscholar   +1 more source