Results 41 to 50 of about 6,275 (177)

Neuromodulation in the treatment of symptoms of spinal cord injury

Journal of Education, Health and Sport, 2020
Introduction and purpose: Spinal cord injury may be associated with loss of motor and sensory functions, autonomic system functions and chronic pain.
Dominik Niemirski, Piotr Machowiec, Mateusz Komisarczuk, Marcela Maksymowicz, Patryk Leszczyk, Halina Piecewicz-Szczęsna   +5 more
doaj   +1 more source

Transcutaneous Spinal Cord Stimulation Attenuates Blood Pressure Drops in Orthostasis. [PDF]

Life (Basel), 2022
Orthostatic hypotension is a complex medical problem with various underlying pathogenic mechanisms and limited modalities for its correction. Since transcutaneous spinal cord stimulation (t-SCS) leads to immediate blood pressure (BP) elevation in a supine position, we suggested that t-SCS may attenuate blood pressure drops in orthostasis.
Beliaeva NN, Moshonkina TR, Mamontov OV, Zharova EN, Condori Leandro HI, Gasimova NZ, Mikhaylov EN.   +6 more
europepmc   +4 more sources

Influence of Spine Curvature on the Efficacy of Transcutaneous Lumbar Spinal Cord Stimulation [PDF]

Journal of Clinical Medicine, 2021
Transcutaneous spinal cord stimulation is a non-invasive method for neuromodulation of sensorimotor function. Its main mechanism of action results from the activation of afferent fibers in the posterior roots—the same structures as targeted by epidural stimulation.
Veronika E. Binder, Ursula S. Hofstoetter, Anna Rienmüller, Zoltán Száva, Matthias J. Krenn, Karen Minassian, Simon M. Danner   +6 more
openaire   +2 more sources

Priming locomotor training with transspinal stimulation in people with spinal cord injury: study protocol of a randomized clinical trial

Trials, 2023
Background The seemingly simple tasks of standing and walking require continuous integration of complex spinal reflex circuits between descending motor commands and ascending sensory inputs. Spinal cord injury greatly impairs standing and walking ability,
Andreas Skiadopoulos, Grace O. Famodimu, Shammah K. Solomon, Parul Agarwal, Noam Y. Harel, Maria Knikou   +5 more
doaj   +1 more source

Common neural structures activated by epidural and transcutaneous lumbar spinal cord stimulation: Elicitation of posterior root-muscle reflexes. [PDF]

PLoS ONE, 2018
Epidural electrical stimulation of the lumbar spinal cord is currently regaining momentum as a neuromodulation intervention in spinal cord injury (SCI) to modify dysregulated sensorimotor functions and augment residual motor capacity.
Ursula S Hofstoetter, Brigitta Freundl, Heinrich Binder, Karen Minassian   +3 more
doaj   +1 more source

First Use of Non-Invasive Spinal Cord Stimulation in Motor Rehabilitation of Children with Spinal Muscular Atrophy

Life, 2023
Spinal muscular atrophy (SMA) is characterized by the degeneration of spinal alpha motorneurons. Nusinersen demonstrated good efficacy in the early disease phases.
Anton Novikov, Maria Maldova, Natalia Shandybina, Ivan Shalmiev, Elena Shoshina, Natalia Epoyan, Tatiana Moshonkina   +6 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

From brain to spinal cord: neuromodulation by direct current stimulation and its promising effects as a treatment option for restless legs syndrome

Frontiers in Neurology
Neuromodulation is a fast-growing field of mostly non-invasive therapies, which includes spinal cord stimulation (SCS), transcranial direct current stimulation (tDCS), vagal nerve stimulation (VNS), peripheral nerve stimulation, transcranial magnetic ...
Christina A. H. Dirks, Cornelius G. Bachmann   +1 more
doaj   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Different Factors Influencing Postural Stability during Transcutaneous Electrical Stimulation of the Cervical Spinal Cord

Journal of Functional Morphology and Kinesiology
Transcutaneous spinal cord stimulation (tSCS) is a promising noninvasive alternative to epidural stimulation. However, further studies are needed to clarify how tSCS affects postural control.
Leisan Bikchentaeva, Margarita Nikulina, Anna Shulman, Maxim Baltin, Angelina Zheltukhina, Elena Semenova, Viktoriya Smirnova, Svetlana Klepikova, Tatyana Baltina   +8 more
doaj   +1 more source