Results 51 to 60 of about 6,275 (177)

SPG4 Hereditary Spastic Paraplegia: From Etiology to Therapy

Movement Disorders, EarlyView.
Abstract Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group of heritable neurodegenerative disorders resulting from mutations in a wide variety of genes. HSP locomotor symptoms include lower limb weakness and spasticity that arise from progressive degeneration of corticospinal axons projecting from the motor cortex to the distal ...
Emanuela Piermarini, Peter W. Baas
wiley   +1 more source

Cortical and Subcortical Effects of Transcutaneous Spinal Cord Stimulation in Humans with Tetraplegia [PDF]

The Journal of Neuroscience, 2020
An increasing number of studies supports the view that transcutaneous electrical stimulation of the spinal cord (TESS) promotes functional recovery in humans with spinal cord injury (SCI). However, the neural mechanisms contributing to these effects remain poorly understood.
Francisco D. Benavides, Hang Jin Jo, Henrik Lundell, V. Reggie Edgerton, Yuri Gerasimenko, Monica A. Perez   +5 more
openaire   +2 more sources

Transcutaneous spinal direct current stimulation (tsDCS) does not affect postural sway of young and healthy subjects during quiet upright standing.

PLoS ONE, 2022
Transcutaneous spinal direct current stimulation (tsDCS) is an effective non-invasive spinal cord electrical stimulation technique to induce neuromodulation of local and distal neural circuits of the central nervous system (CNS).
Felipe Fava de Lima, Cristiano Rocha Silva, Andre Fabio Kohn   +2 more
doaj   +1 more source

Electrical Modalities in the Rehabilitation of Peripheral Nerve Injuries: State of the Literature and Current Clinical Applications

Muscle &Nerve, EarlyView.
ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith, Kirsten M. Schlosser, Ranee Munaim, Stephanie H. Vu, JulieAnn H. Uh, Yusha K. Liu   +5 more
wiley   +1 more source

Spinal cord stimulation as a novel neuromodulation strategy for enhancing language recovery in post-stroke aphasia: a hypothesis

Frontiers in Human Neuroscience
Post-stroke aphasia is a debilitating language disorder that significantly impairs communication and quality of life. Although speech therapy and non-invasive brain stimulation techniques such as repetitive transcranial magnetic stimulation (rTMS) and ...
Di Lu, Di Lu, Mingming Zhao, Mingming Zhao, Xin Yan, Xin Yan, Shuyun Wang, Shuyun Wang, Zhitao Li, Feng Yin, Feng Yin   +10 more
doaj   +1 more source

Targeted Muscle Reinnervation for Intuitive Prosthetic Control

Muscle &Nerve, EarlyView.
ABSTRACT The convergence of medical and technological advances has led to a substantial expansion of therapeutic approaches for patients with limb amputations. Targeted muscle reinnervation (TMR) is one of the strategies to improve control of bionic arms and has been applied for more than two decades. Through surgical rewiring of the nerves responsible
Nitay Maile, Laura Ferrante, Dario Farina, Ulla Al Dabbass, Oskar C. Aszmann, Vlad Tereshenko   +5 more
wiley   +1 more source

Long‐Term Outcomes of Sacral Neuromodulation Explantation: A 12‐Year Experience at a High‐Volume Tertiary Center

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Sacral neuromodulation (SNM) is a therapeutic option offered to patients with idiopathic overactive bladder (OAB) or non‐obstructive urinary retention, as an alternative treatment for refractory medical management. It allows for electrical stimulation of inhibitory circuits that modulate the micturition reflex and improve lower ...
Carly Fiorido, Mario Henrique Bitar Siqueira, Mohammed Aldoukhi, Nojoud Alamri, Eviatar Fields, Naeem Bhojani, Bilal Chughtai, Omar Buksh, Sagi Shprits, Katherine Lajkosz, Dean Elterman   +10 more
wiley   +1 more source

Transcutaneous spinal stimulation as a therapeutic strategy for spinal cord injury: state of the art

Journal of Neurorestoratology, 2015
Leandro H Grecco,1,3,4,* Shasha Li,1,5,* Sarah Michel,1,6,* Laura Castillo-Saavedra,1 Andoni Mourdoukoutas,7 Marom Bikson,7 Felipe Fregni1,21Spaulding Neuromodulation Center, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA ...
Grecco LH, Li S, Michel S, Castillo-Saavedra L, Mourdoukoutas A, Bikson M, Fregni F   +6 more
doaj  

One‐Year Transcutaneous Tibial Nerve Stimulation Treatment Persistence in Lower Urinary Tract Dysfunction: Clinical and Urodynamic Associated Factors in a Prospective Observational Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To assess 1‐year Transcutaneous Tibial Nerve Stimulation (TTNS) treatment persistence in routine clinical care and to explore clinical and urodynamic factors associated with treatment persistence in patients with lower urinary tract dysfunction (LUTD).
Damien Prat, Evelyne Castel‐Lacanal, Thibaut Brierre, Gaetane Foures, Camille Cormier, Xavier De Boissezon, David Gasq, Philippe Marque, Xavier Gamé, Emmeline Montané   +9 more
wiley   +1 more source

Evaluating the efficacy of obturator cryoneurolysis for hip adductor spasticity: An observational, prospective study

PM&R, EarlyView.
Abstract Background Hip adductor spasticity is a common affliction among patients with disorders of the central nervous system. Cryoneurolysis is a novel intervention for spasticity involving the application of extreme cold to a nerve. This induces axonal breakdown, relieving spasticity.
Fraser MacRae, Mahdis Hashemi, Paul Winston   +2 more
wiley   +1 more source