Results 61 to 70 of about 6,275 (177)

Minimal handgrip force is needed for transcutaneous electrical stimulation to improve hand functions of patients with severe spinal cord injury

Scientific Reports, 2022
Spinal cord stimulation enhanced restoration of motor function following spinal cord injury (SCI) in unblinded studies. To determine whether training combined with transcutaneous electrical spinal cord stimulation (tSCS), with or without systemic ...
Ruyi Huang, Ali A. Nikooyan, Lisa D. Moore, Sharon Zdunowski, Erika Morikawa, Tiffany Sierro, Dimitry Sayenko, Parag Gad, Tali Homsey, Timothy Le, Meghna A. Madhavan, Marina Abdelshahid, Martina Abdelshahid, Yan Zhou, Mark R. Nuwer, Majid Sarrafzadeh, V. Reggie Edgerton, James C. Leiter, Daniel C. Lu   +18 more
doaj   +1 more source

Innovative technologies for gait rehabilitation in incomplete spinal cord injury: A systematic review and meta‐analysis

PM&R, EarlyView.
Abstract Objective This systematic review and meta‐analysis aimed to synthesize the current evidence on the efficacy of various technological interventions for gait rehabilitation in adults with incomplete spinal cord injury (iSCI). Literature survey MEDLINE (accessed by PubMed), Embase, Cochrane Central Register of Controlled Trials (Cochrane CENTRAL),
Emerson de Carvalho, Thainara Cruz da Rosa, Maira Jaqueline da Cunha, Aline S. Pagnussat   +3 more
wiley   +1 more source

Cervical Spinal Cord Stimulation for Functional Rehabilitation After Spinal Cord Injury: A Systematic Review of Preclinical and Clinical Studies

Life
Cervical spinal cord injury causes severe functional impairment with limited spontaneous recovery, and while spinal cord stimulation has emerged as a promising neuromodulatory strategy, evidence for cervical applications remains fragmented.
Maximilian C. Wankner, Veerle Visser-Vandewalle, Pablo Andrade, Petra Heiden   +3 more
doaj   +1 more source

Effect of transcutaneous electrical nerve stimulation on physical activity and pain evaluation in osteoarthritic dogs

Veterinary Record, EarlyView.
Abstract Background Osteoarthritis (OA) causes chronic pain and reduces welfare in dogs. Standard treatments may be inadequate or associated with adverse effects, prompting investigation of alternative therapies. Transcutaneous electrical nerve stimulation (TENS) is a non‐pharmacological pain management method, but evidence for its efficacy in canine ...
Anja Pedersen, Johanna Penell, Emil Olsen, Heli Hyytiäinen, Franck Forterre, Anna Bergh   +5 more
wiley   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Neuropathic pain in cerebral palsy and related genetic conditions: A scoping review of prevalence, characteristics, and management

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To map existing evidence on neuropathic pain in cerebral palsy (CP) and related genetic conditions, including prevalence, descriptors, assessment methods, and management. Method Following prospective registration, five databases (Ovid MEDLINE, Embase, CINAHL, Web of Science, Google Scholar) were searched in June 2025.
Aayushi Khillan, Sanya Verma, Hannah Yeomans, Karen Bau, Caitlin Doyle, Monica S. Cooper, David J. Amor, Carolyn Berryman, Adrienne Harvey   +8 more
wiley   +1 more source

Case report: Virtual reality-based arm and leg cycling combined with transcutaneous electrical spinal cord stimulation for early treatment of a cervical spinal cord injured patient

Frontiers in Neuroscience
Spinal cord injury is a condition affecting the central nervous system, causing different levels of dysfunction below the point of nerve damage. A 50-year-old woman suffered a neck injury as a result of a car accident. After undergoing posterior cervical
Xiaolei Chu, Shuaiyi Liu, Xiaoxuan Zhao, Tao Liu, Zheng Xing, Qingwen Li, Qi Li   +6 more
doaj   +1 more source

Electromyography (EMG)-triggered transcutaneous spinal cord and hip stimulation for gait rehabilitation in persons with chronic stroke: a randomized, controlled trial

Journal of NeuroEngineering and Rehabilitation
Background Transcutaneous spinal stimulation has been applied to gait rehabilitation for persons with neurological diseases. The authors developed electromyography-triggered transcutaneous spinal cord and hip stimulation for gait rehabilitation and ...
Mami Tani, Tomofumi Yamaguchi, Kaoru Honaga, Yoko Takahashi, Hidemi Kono, Yuhei Murakami, Reina Isayama, Koshiro Haruyama, Yuji Fujino, Tadamitsu Matsuda, Issei Fukunaga, Masaaki Hori, Akira Tanuma, Futoshi Wada, Kozo Hatori, Toshiyuki Fujiwara   +15 more
doaj   +1 more source