Results 91 to 100 of about 8,521 (212)

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Repeated transspinal stimulation decreases soleus H-reflex excitability and restores spinal inhibition in human spinal cord injury.

PLoS ONE, 2019
Transcutaneous spinal cord or transspinal stimulation over the thoracolumbar enlargement, the spinal location of motoneurons innervating leg muscles, modulates neural circuits engaged in the control of movement.
Maria Knikou, Lynda M Murray
doaj   +1 more source

Neuropathic pain in cerebral palsy and related genetic conditions: A scoping review of prevalence, characteristics, and management

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To map existing evidence on neuropathic pain in cerebral palsy (CP) and related genetic conditions, including prevalence, descriptors, assessment methods, and management. Method Following prospective registration, five databases (Ovid MEDLINE, Embase, CINAHL, Web of Science, Google Scholar) were searched in June 2025.
Aayushi Khillan, Sanya Verma, Hannah Yeomans, Karen Bau, Caitlin Doyle, Monica S. Cooper, David J. Amor, Carolyn Berryman, Adrienne Harvey   +8 more
wiley   +1 more source

Efficacy and mechanisms of neuromodulation in the treatment of irritable bowel syndrome

Bioelectronic Medicine
Disorders of gut-brain interaction (DGBI), including irritable bowel syndrome (IBS), have a significant impact on patients, reducing their quality of life and work efficiency.
Kaijie Wang, Md Jahangir Alam, Xinya Lan, Fei Li, Jiande D. Z. Chen   +4 more
doaj   +1 more source

On the use of sham transcutaneous spinal cord stimulation in spinal cord injury clinical trials

Brain
Kramer et al. examine the reasons put forth by investigators for excluding a sham condition in trials of neuromodulation therapies for individuals with spinal cord injury. They conclude that current dogma does not justify this design, and emphasize the need for future trials to include appropriate controls.
Kramer, John L K, Lam, Tania, Rossi, Fabio M V, Illes, Judy   +3 more
openaire   +2 more sources

Effects of Transcutaneous Electrical Nerve Stimulation on Pain and Menstrual Symptoms in Primary Dysmenorrhea: A Placebo‐Controlled Study

Journal of Midwifery &Women's Health, EarlyView.
Introduction Primary dysmenorrhea, with a prevalence of 45% to 95%, is a common gynecological condition that significantly affects women's daily functioning and quality of life. Methods This randomized, single‐masked study compared the effects of transcutaneous electrical nerve stimulation (TENS) on pain intensity and menstrual symptoms in women with ...
Esra Ünal
wiley   +1 more source

Cervical Spinal Cord Stimulation for Functional Rehabilitation After Spinal Cord Injury: A Systematic Review of Preclinical and Clinical Studies

Life
Cervical spinal cord injury causes severe functional impairment with limited spontaneous recovery, and while spinal cord stimulation has emerged as a promising neuromodulatory strategy, evidence for cervical applications remains fragmented.
Maximilian C. Wankner, Veerle Visser-Vandewalle, Pablo Andrade, Petra Heiden   +3 more
doaj   +1 more source

Characterizing neurological status in individuals with tetraplegia using transcutaneous spinal stimulation. [PDF]

Sci Rep, 2023
Oh J, Scheffler MS, Martin CA, Dinh J, Sheynin J, Steele AG, Sayenko DG.   +6 more
europepmc   +1 more source

Comparison of the Effects of Different Manual Therapy Techniques on Mandibular Mobility, Cervical Joint Position Sense, Jaw Function and Anxiety Levels in Individuals With Rheumatoid Arthritis and Temporomandibular Disorders: A Randomized Controlled Trial

Journal of Oral Rehabilitation, EarlyView.
Joint mobilization and soft tissue mobilization improved mandibular mobility, cervical proprioception, jaw function and anxiety levels in rheumatoid arthritis patients with temporomandibular disorders compared to the control group. ABSTRACT Objective This study aimed to compare the effects of soft tissue mobilization (STM) and joint mobilization (JM ...
Kübra Aktaş, Hakan Polat, Tuba Maden, Burhan Fatih Koçyiğit   +3 more
wiley   +1 more source

Improved Sensation With Transcutaneous Spinal Cord Stimulation Following Chronic Spinal Cord Injury

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Following spinal cord injury (SCI), recovery of sensation is often neglected despite its critical roles in motor task execution and injury prevention. The Up-LIFT trial recently found targeted transcutaneous spinal cord stimulation (tSCS) combined with rehabilitation significantly improved sensation in addition to upper extremity (UE) strength and ...
Jessica D'Amico, Kristen Gelenitis, Fatma Inanici, Edelle C. Field-Fote, Candace Tefertiller, Chet Moritz   +5 more
openaire   +2 more sources