Results 81 to 90 of about 18,129 (271)

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Analysis of current density and related parameters in spinal cord stimulation [PDF]

, 1998
A volume conductor model of the spinal cord and surrounding anatomical structures is used to calculate current (and current density) charge per pulse, and maximum charge density per pulse at the contact surface of the electrode in the dorsal epidural ...
Boom, Herman B.K., Holsheimer, Jan, Wesselink, Wilbert A.   +2 more
core   +3 more sources

Fish Scales: A Multifunctional Biomaterial from Nature

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley   +1 more source

Electromyography (EMG)-triggered transcutaneous spinal cord and hip stimulation for gait rehabilitation in persons with chronic stroke: a randomized, controlled trial

Journal of NeuroEngineering and Rehabilitation
Background Transcutaneous spinal stimulation has been applied to gait rehabilitation for persons with neurological diseases. The authors developed electromyography-triggered transcutaneous spinal cord and hip stimulation for gait rehabilitation and ...
Mami Tani, Tomofumi Yamaguchi, Kaoru Honaga, Yoko Takahashi, Hidemi Kono, Yuhei Murakami, Reina Isayama, Koshiro Haruyama, Yuji Fujino, Tadamitsu Matsuda, Issei Fukunaga, Masaaki Hori, Akira Tanuma, Futoshi Wada, Kozo Hatori, Toshiyuki Fujiwara   +15 more
doaj   +1 more source

Smart control for functional electrical stimulation with optimal pulse intensity

Current Directions in Biomedical Engineering, 2016
Transcutaneous electrical stimulation is a common treatment option for patients suffering from spinal cord injury or stroke. Two major difficulties arise when employing electrical stimulation in patients: Accurate stimulation electrode placement and ...
Reinert Aljoscha, Loitz Jan C., Quandt Fanny, Schroeder Dietmar, Krautschneider Wolfgang H.   +4 more
doaj   +1 more source

Mitigation of nociception via transganglionic degenerative atrophy: possible mechanism of vinpocetine-induced blockade of retrograde axoplasmic transport [PDF]

, 2008
I Sverige har ett förväntat ökande gap mellan tillgängliga resurser och ökade behandlingsmöjligheter satt fokus på evidensbaserad prioritering. Problem har emellertid konstaterats inom områden med svag evidensgrund och oklar eller kontroversiell ...
Csillik, Bertalan, Mihály, András, Krisztin-Péva, Beáta, Farkas, Ibolya, Knyihár-Csillik, Erzsébet   +4 more
core   +1 more source

Transcutaneous Spinal Cord Stimulation and Motor Rehabilitation in Spinal Cord Injury: A Systematic Review [PDF]

Neurorehabilitation and Neural Repair, 2019
Background. Epidural spinal electrical stimulation at the lumbar spinal level evokes rhythmic muscle activation of lower-limb antagonists, attributed to the central pattern generator. However, the efficacy of noninvasive spinal stimulation for the activation of lower-limb muscles is not yet clear.
Alvaro Megía García, Diego Serrano-Muñoz, Julian Taylor, Juan Avendaño-Coy, Julio Gómez-Soriano   +4 more
openaire   +3 more sources

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee, Rachel C. Hector, Lynn Pezzanite, Eric Gilleland, Marlis L. Rezende   +4 more
wiley   +1 more source

Neuromodulation of the Cardiac Autonomic Nervous System for Arrhythmia Treatment

Biomedicines
This review explores current and emerging neuromodulation techniques targeting the cardiac autonomic nervous system for the treatment and prevention of atrial and ventricular arrhythmias. Arrhythmias remain a significant cause of morbidity and mortality,
Benjamin Wong, Yuki Kuwabara, Siamak Salavatian   +2 more
doaj   +1 more source