Results 141 to 150 of about 152,119 (385)

Mathematical Modelling of Variable Porosity Coatings for Dual Drug Delivery [PDF]

open access: yes, 2017
In this paper we describe a theoretical mathematical model of dual drug delivery from a durable polymer coated medical device. We demonstrate how the release rate of each drug may in principle be controlled by altering the initial loading configuration
McGinty, Sean, Pontrelli, Giuseppe
core  

Cell‐Stress‐Free Percutaneous Bioelectrodes

open access: yesAdvanced Materials, EarlyView.
A structurally adaptive soft microneedle bioelectrode is developed with an effervescent sacrificial core that dissolves after insertion, leaving an ultrathin and highly compliant electrode integrated with skin. This design enables ultra‐flexible, cell‐stress‐free, stable, and high‐fidelity electrophysiological monitoring under dynamic conditions such ...
Jungho Lee   +14 more
wiley   +1 more source

Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial [PDF]

open access: gold, 2023
Jason P. Appleton   +21 more
openalex   +1 more source

Colloidal Heterostructures Enable Interfacial Transport of Immiscible Molecules in Printable Organohydrogels

open access: yesAdvanced Materials, EarlyView.
Multiphase printable organohydrogels with tunable microstructures are developed to control molecular transport pathways for immiscible cargo. The tortuosity and domain size of the colloidal phases are tuned by adjusting temperature and shear during processing, which enables the tailoring of diffusion kinetics due to different transport pathways.
Riley E. Dowdy‐Green   +4 more
wiley   +1 more source

Transferosomal gel for transdermal delivery of insulin: Formulation development and ex vivo permeation study

open access: diamond, 2023
Venkatasamy Prashanthini   +7 more
openalex   +1 more source

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

open access: yesAdvanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon   +21 more
wiley   +1 more source

An AI‐embedded, Wearable Dual Closed‐Loop Insulin Delivery System for Precision Diabetes Management

open access: yesAdvanced Materials, EarlyView.
A wearable dual closed‐loop drug delivery system for diabetes management is presented, featuring an adaptive, on‐body trained edge AI algorithm for precise insulin delivery, which enhances therapeutic accuracy from 92.10% to 98.82%. Abstract Effective blood glucose management is an increasing demand worldwide.
Xuecheng He   +12 more
wiley   +1 more source

Different effects of oral and transdermal hormone replacement therapies on Factor IX, APC resistance, t-PA, PAI and C- reactive protein - a cross-sectional population survey [PDF]

open access: yes, 2001
The effects of hormone replacement therapy (HRT) on thrombosis risk, thrombotic variables, and the inflammatory marker C- reactive protein (CRP) may vary by route of administration (oral versus transdermal).
Lowe, G.D.O.   +5 more
core  

Framework nucleic acids as programmable carrier for transdermal drug delivery

open access: yesNature Communications, 2019
DNA nanostructures are promising drug carriers with their intrinsic biocompatibility, uniformity and versatility. However, rapid serum disintegration leads to low bioavailability at targeted sites following systemic administration, hindering their ...
Christian Wiraja   +11 more
semanticscholar   +1 more source

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