Results 11 to 20 of about 81,011 (193)

Recent Advancement of Medical Patch for Transdermal Drug Delivery

Medicina, 2023
Transdermal patches are a non-invasive method of drug administration. It is an adhesive patch designed to deliver a specific dose of medication through the skin and into the bloodstream throughout the body.
W. Wong, Kuan Ping Ang, G. Sethi, C. Looi   +3 more
semanticscholar   +1 more source

Efektivitas Patch Transdermal Ekstrak Etanol Daun Insulin (Smallanthus sonchifolius) Terhadap Kadar Glukosa Darah dan Histopatologi Pankreas Tikus Putih

JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2023
Diabetes melitus adalah penyakit metabolik yang ditandai dengan hiperglikemia akibat kelainan sekresi insulin, kerja insulin atau keduanya. Salah satu permasalahan yang dihadapi dalam pengobatan pasien diabetes adalah kepatuhan terhadap terapi obat. Daun
Ni Putu Pirna Wijayanti, Lucia Hendriati, Iwan Sahrial Hamid, Teguh Widodo, Suryo Kuncorojakti   +4 more
doaj   +1 more source

Microneedle for transdermal drug delivery: current trends and fabrication

Journal of Pharmaceutical Investigation, 2021
Transdermal delivery has the advantage of bypassing the first-pass effect and allowing sustained release of the drug. However, the drug delivery is limited owing to the barrier created by the stratum corneum.
J. Jung, S. Jin
semanticscholar   +1 more source

The Optimization of a Dimenhydrinate Transdermal Patch Formulation Based on the Quantitative Analysis of In Vitro Release Data by DDSolver through Skin Penetration Studies

Scientia Pharmaceutica, 2021
Dimenhydrinate is an over-the-counter medication that is used to relieve nausea, vomiting, and vertigo caused by motion sickness. It has a short elimination half-life, possibly due to its first-pass metabolism.
Bazigha K. Abdul Rasool, Amira A. Mohammed, Yasmein Y. Salem   +2 more
doaj   +1 more source

Ibuprofen-Loaded Chitosan–Lipid Nanoconjugate Hydrogel with Gum Arabic: Green Synthesis, Characterisation, In Vitro Kinetics Mechanistic Release Study and PGE2 Production Test

Gels, 2021
Ibuprofen is a well-known non-steroidal anti-inflammatory (NSAID) medicine that is often used to treat inflammation in general. When given orally, it produces gastrointestinal issues which lead to lower patient compliance.
Syed Mahmood, Samah Hamed Almurisi, Khater AL-Japairai, Ayah Rebhi Hilles, Walla Alelwani, Azzah M. Bannunah, Farhan Alshammari, Fawaz Alheibshy   +7 more
doaj   +1 more source

Effect of Penetration Enhancers on Transdermal Delivery of Oxcarbazepine, an Antiepileptic Drug Using Microemulsions

Pharmaceutics, 2023
Oxcarbazepine (OXC) is an anticonvulsant drug, indicated for the treatment of the neurological disorder, epilepsy. The objective of the present study was to evaluate the transdermal delivery of OXC from microemulsions using different penetration ...
Amitkumar Virani, Vinam Puri, Hana Mohd, Bozena Michniak-Kohn   +3 more
doaj   +1 more source

Microneedle-Mediated Transdermal Delivery of Biopharmaceuticals

Pharmaceutics, 2023
Transdermal delivery provides numerous benefits over conventional routes of administration. However, this strategy is generally limited to a few molecules with specific physicochemical properties (low molecular weight, high potency, and moderate ...
Hiep X. Nguyen, C. Nguyen
semanticscholar   +1 more source

Functional nano-systems for transdermal drug delivery and skin therapy

Nanoscale Advances, 2023
Transdermal drug delivery is one of the least intrusive and patient-friendly ways for therapeutic agent administration. Recently, functional nano-systems have been demonstrated as one of the most promising strategies to treat skin diseases by improving ...
Lijun Liu, Wen-yan Zhao, Qingming Ma, Yang Gao, Weijiang Wang, Xuan Zhang, Yunxia Dong, Tingting Zhang, Yan Liang, Shangcong Han, Jie Cao, Xinyu Wang, Wentao Sun, Haifeng Ma, Yong Sun   +14 more
semanticscholar   +1 more source

O/W microemulsion droplets diffuse through hydrogel network to achieve enhanced transdermal drug delivery

Drug Delivery, 2021
To overcome the poor water solubility of total flavones of Arisaematis rhizoma, microemulsions (MEs) can be used as a carrier for transdermal administration to promote their solubilization and skin permeability.
Lina Shen, Xiaolin Hou, Zhi Wang, Teng Guo, Zehui He, Shuyao Ruan, Zhenda Liu, Hang Ruan, Yongtai Zhang, Nianping Feng   +9 more
doaj   +1 more source

Advanced nanocarrier- and microneedle-based transdermal drug delivery strategies for skin diseases treatment

Theranostics, 2022
Skin diseases are the fourth leading cause of nonfatal and chronic skin diseases, acting as a global burden and affecting the world economy. Skin diseases severely impact the patients' quality of life and have influenced their physical and mental state ...
Fei Qu, Rui Geng, Yijing Liu, Jintao Zhu
semanticscholar   +1 more source