Results 21 to 30 of about 81,011 (193)

Strategies for Improving Transdermal Administration: New Approaches to Controlled Drug Release

Pharmaceutics, 2023
In this work, we aim to address several strategies to improve transdermal drug delivery, such as iontophoresis, sonophoresis, electroporation and micron. We also propose a review of some transdermal patches and their applications in medicine.
Olimpia Dumitriu Buzia, A. Paduraru, C. Stefan, M. Dinu, Dorin-Ioan Cocoș, L. Nwabudike, A. Tatu   +6 more
semanticscholar   +1 more source

Applications and recent advances in transdermal drug delivery systems for the treatment of rheumatoid arthritis

Acta Pharmaceutica Sinica B, 2023
Rheumatoid arthritis is a chronic, systemic autoimmune disease predominantly based on joint lesions with an extremely high disability and deformity rate.
Yuyi Xu, Ming Zhao, Jinxue Cao, Ting Fang, Jian Zhang, Yanli Zhen, Fangling Wu, Xiaohui Yu, Yaming Liu, Ji Li, Dongkai Wang   +10 more
semanticscholar   +1 more source

The effect of transdermal flunixin meglumine on blood cortisol levels in dairy calves after cautery disbudding with local anesthesia

Journal of Dairy Science, 2022
: The objective of this study was to evaluate the effect of the nonsteroidal anti-inflammatory drug transdermal flunixin meglumine (Finadyne Transdermal) on plasma cortisol, average daily weight gain, and standing and lying behavior of calves, when given
M. Röder, W. Heuwieser, S. Borchardt, J.L. Plenio, R. Palme, F. Sutter   +5 more
doaj   +1 more source

Iontophoresis-driven microneedle patch for the active transdermal delivery of vaccine macromolecules

Microsystems & Nanoengineering, 2023
COVID-19 has seriously threatened public health, and transdermal vaccination is an effective way to prevent pathogen infection. Microneedles (MNs) can damage the stratum corneum to allow passive diffusion of vaccine macromolecules, but the delivery ...
Ying Zheng, Rui Ye, Xia Gong, Jingbo Yang, Bin Liu, Yunsheng Xu, Gang Nie, Xi Xie, Lelun Jiang   +8 more
semanticscholar   +1 more source

Transdermal estrogen gel vs oral estrogen after hysteroscopy for intrauterine adhesion separation: A prospective randomized study

Frontiers in Endocrinology, 2023
BackgroundThis randomized controlled trial (RCT) aimed to compare two different routes of postoperative estrogen treatment on the improvements of menstruation, postoperative endometrial thickness, and fertility outcomes in patients with moderate to ...
Tianjin Yi, Tianjin Yi, Xiaofang Zhang, Xiaofang Zhang, Vani Gupta, Li Li, Li Li, Qian Zhong, Qian Zhong   +8 more
doaj   +1 more source

Plant Exosome-like Nanoparticles as Biological Shuttles for Transdermal Drug Delivery

Bioengineering, 2023
Exosomes act as emerging transdermal drug delivery vehicles with high deformability and excellent permeability, which can be used to deliver various small-molecule drugs and macromolecular drugs and increase the transdermal and dermal retention of drugs,
Ye Wang, Yongsheng Wei, Hui Liao, Hongwei Fu, Xiaobin Yang, Qiu Xiang, Shu Zhang   +6 more
semanticscholar   +1 more source

Ion-Pair Compounds of Strychnine for Enhancing Skin Permeability: Influencing the Transdermal Processes In Vitro Based on Molecular Simulation

Pharmaceuticals, 2021
This research aimed to explore how Strychnine (Str) ion-pair compounds affect the in vitro transdermal process. In order to prevent the influence of different functional groups on skin permeation, seven homologous fatty acids were selected to form ion ...
Lili He, Di Xiong, Lan Ma, Yan Liang, Teng Zhang, Zhiming Wu, Huaibo Tang, Xuewen Wu   +7 more
doaj   +1 more source

Beneath the Skin: A Review of Current Trends and Future Prospects of Transdermal Drug Delivery Systems

Pharmaceutics, 2022
The ideal drug delivery system has a bioavailability comparable to parenteral dosage forms but is as convenient and easy to use for the patient as oral solid dosage forms.
A. Alkilani, Jehad Nasereddin, Rania Hamed, Sukaina Nimrawi, Ghaid Hussein, Hadeel Abo-Zour, R. Donnelly   +6 more
semanticscholar   +1 more source

Transfersomes: A Promising Nanoencapsulation Technique for Transdermal Drug Delivery

Pharmaceutics, 2020
Transdermal delivery systems have gained much interest in recent years owing to their advantages compared to conventional oral and parenteral delivery systems.
Shakthi Apsara Thejani Opatha, Varin Titapiwatanakun, Romchat Chutoprapat   +2 more
semanticscholar   +1 more source

Transdermal electroosmotic flow generated by a porous microneedle array patch

Nature Communications, 2021
A microneedle array is an attractive option for a minimally invasive means to break through the skin barrier for efficient transdermal drug delivery.
Shinya Kusama, Kaito Sato, Yuuya Matsui, Natsumi Kimura, H. Abe, S. Yoshida, M. Nishizawa   +6 more
semanticscholar   +1 more source