Results 21 to 30 of about 110,346 (342)

Amorphization of Drugs for Transdermal Delivery-a Recent Update

open access: yesPharmaceutics, 2022
Amorphous solid dispersion is a popular formulation approach for orally administered poorly water-soluble drugs, especially for BCS class II. But oral delivery could not be an automatic choice for some drugs with high first-pass metabolism susceptibility.
Bappaditya Chatterjee   +3 more
doaj   +1 more source

Hormone replacement therapy [PDF]

open access: yes, 2012
Martha Hickey, Jane Elliott, Sonia Louise ...
Davison, S., Elliott, C., Hickey, M.
core   +2 more sources

A Note on the Trandermal Delivery of Clenbuterol [PDF]

open access: yes, 1992
A modified diffusion/compartmental model has been used to simulate the transdermal uptake of clenbuterol from a matrix-type delivery device. The application of a fresh device every 7 days was found to produce a pseudo-steady state drug plasma profile ...
Göpferich, Achim, Lee, Geoffrey
core   +1 more source

Development of a Topical Resveratrol Formulation for Commercial Applications Using Dendrimer Nanotechnology

open access: yesMolecules, 2017
Resveratrol (RSV) is well known for its anti-oxidant and anti-aging properties. However, resveratrol is insoluble in water and has stability issues. Recently, efforts were placed to prepare a resveratrol-based advanced anti-aging topical product but it ...
Tyler Pentek   +3 more
doaj   +1 more source

Predicting Skin Permeability by means of Computational Approaches : Reliability and Caveats in Pharmaceutical Studies [PDF]

open access: yes, 2019
© 2019 American Chemical Society.The skin is the main barrier between the internal body environment and the external one. The characteristics of this barrier and its properties are able to modify and affect drug delivery and chemical toxicity parameters.
Almerico, Anna Maria   +5 more
core   +2 more sources

The challenge of perioperative pain management in opioid-tolerant patients [PDF]

open access: yes, 2017
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F   +9 more
core   +6 more sources

Physiologically-based pharmacokinetic simulations in pharmacotherapy: selection of the optimal administration route for exogenous melatonin

open access: yesADMET and DMPK, 2019
The benefits of melatonin on human body are drawing increasing attention from several researchers in different fields. While its role as cure for sleep disturbances (e.g., jet lag, insomnia) is well documented and established, new functions in ...
Adriana Savoca, Davide Manca
doaj   +1 more source

Transdermal estrogen gel vs oral estrogen after hysteroscopy for intrauterine adhesion separation: A prospective randomized study

open access: yesFrontiers in Endocrinology, 2023
BackgroundThis randomized controlled trial (RCT) aimed to compare two different routes of postoperative estrogen treatment on the improvements of menstruation, postoperative endometrial thickness, and fertility outcomes in patients with moderate to ...
Tianjin Yi   +8 more
doaj   +1 more source

Metabolic, inflammatory and haemostatic effects of a low-dose continuous combined HRT in women with type 2 diabetes: potentially safer with respect to vascular risk? [PDF]

open access: yes, 2003
BACKGROUND Conventional hormone replacement therapy (HRT) containing conjugated equine oestrogen (CEE) and medroxyprogesterone acetate (MPA) increases triglyceride, C- reactive protein (CRP) and coagulation Factor VII concentrations, potentially ...
Alan J. Jaap   +46 more
core   +1 more source

Efektivitas Patch Transdermal Ekstrak Etanol Daun Insulin (Smallanthus sonchifolius) Terhadap Kadar Glukosa Darah dan Histopatologi Pankreas Tikus Putih

open access: yesJPSCR: Journal of Pharmaceutical Science and Clinical Research, 2023
Diabetes melitus adalah penyakit metabolik yang ditandai dengan hiperglikemia akibat kelainan sekresi insulin, kerja insulin atau keduanya. Salah satu permasalahan yang dihadapi dalam pengobatan pasien diabetes adalah kepatuhan terhadap terapi obat. Daun
Ni Putu Pirna Wijayanti   +4 more
doaj   +1 more source

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