Results 21 to 30 of about 92,575 (360)

Advanced nanocarrier- and microneedle-based transdermal drug delivery strategies for skin diseases treatment

open access: yesTheranostics, 2022
Skin diseases are the fourth leading cause of nonfatal and chronic skin diseases, acting as a global burden and affecting the world economy. Skin diseases severely impact the patients' quality of life and have influenced their physical and mental state ...
Fei Qu   +3 more
semanticscholar   +1 more source

Microneedle for transdermal drug delivery: current trends and fabrication

open access: yesJournal of Pharmaceutical Investigation, 2021
Transdermal delivery has the advantage of bypassing the first-pass effect and allowing sustained release of the drug. However, the drug delivery is limited owing to the barrier created by the stratum corneum.
J. Jung, S. Jin
semanticscholar   +1 more source

Beneath the Skin: A Review of Current Trends and Future Prospects of Transdermal Drug Delivery Systems

open access: yesPharmaceutics, 2022
The ideal drug delivery system has a bioavailability comparable to parenteral dosage forms but is as convenient and easy to use for the patient as oral solid dosage forms.
A. Alkilani   +6 more
semanticscholar   +1 more source

Transdermal electroosmotic flow generated by a porous microneedle array patch

open access: yesNature Communications, 2021
A microneedle array is an attractive option for a minimally invasive means to break through the skin barrier for efficient transdermal drug delivery.
Shinya Kusama   +6 more
semanticscholar   +1 more source

Microneedle-assisted genome editing: A transdermal strategy of targeting NLRP3 by CRISPR-Cas9 for synergistic therapy of inflammatory skin disorders

open access: yesScience Advances, 2021
Transdermal delivery of genome-editing agents by microneedle promotes the glucocorticoid therapy of inflammatory skin disorders. We report a dissolvable microneedle (MN) patch that can mediate transdermal codelivery of CRISPR-Cas9–based genome-editing ...
Tao Wan, Qi Pan, Y. Ping
semanticscholar   +1 more source

Effects of transdermal versus oral hormone replacement therapy in postmenopause: a systematic review

open access: yesArchives of Gynecology and Obstetrics, 2022
Purpose To summarize available evidence comparing the transdermal and the oral administration routes of hormone replacement therapy (HRT) in postmenopausal women.
Marina Sprem Goldstajn   +9 more
semanticscholar   +1 more source

Transdermal nitroglycerin

open access: yesJournal of the American College of Cardiology, 1989
Journal of the American College of Cardiology 13 (1989) 426-427. doi:10.1016/0735-1097(89)90522-6 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:22:40 ; DOI:10.1016/0735-1097(89)90522-6 ; Page Range: 426 ...
From the College of Medicine, University of Florida, Gainesville, Florida, USA ( host institution )   +1 more
openaire   +3 more sources

Transfersomes: A Promising Nanoencapsulation Technique for Transdermal Drug Delivery

open access: yesPharmaceutics, 2020
Transdermal delivery systems have gained much interest in recent years owing to their advantages compared to conventional oral and parenteral delivery systems.
Shakthi Apsara Thejani Opatha   +2 more
semanticscholar   +1 more source

Transdermal delivery of testosterone [PDF]

open access: yesEuropean Journal of Pharmaceutics and Biopharmaceutics, 2015
Male hypogonadism has been treated with exogenous testosterone since the 1930s. The early transdermal patches of testosterone became available in the 1980s with gel and solution preparations following subsequent decades. This review focusses on the skin permeation characteristics of testosterone, pharmacokinetics following application of transdermal ...
Hadgraft, J, Lane, ME
openaire   +4 more sources

Transdermal drug delivery of labetalol hydrochloride: Feasibility and effect of penetration enhancers

open access: yesJournal of Pharmacy and Bioallied Sciences, 2010
Objectives : The objective of this study is to investigate the feasibility of transdermal drug delivery of Labetalol Hydrochloride (LHCl) and to study the effect of different penetration enhancers on the skin permeability of LHCl.
Saqib Zafar   +3 more
doaj   +1 more source

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