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Journal of the American College of Cardiology 13 (1989) 426-427. doi:10.1016/0735-1097(89)90522-6 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:22:40 ; DOI:10.1016/0735-1097(89)90522-6 ; Page Range: 426 ...
From the College of Medicine, University of Florida, Gainesville, Florida, USA ( host institution ) +1 more
openaire +3 more sources
Amorphization of Drugs for Transdermal Delivery-a Recent Update
Amorphous solid dispersion is a popular formulation approach for orally administered poorly water-soluble drugs, especially for BCS class II. But oral delivery could not be an automatic choice for some drugs with high first-pass metabolism susceptibility.
Bappaditya Chatterjee +3 more
doaj +1 more source
Dermal and Transdermal Drug Delivery through Vesicles and Particles: Preparation and Applications [PDF]
Transdermal delivery over the past decade has become the field of interest for drug delivery due to its various advantages such as no first-pass metabolism, increased drug bioavailability, and easy administration. Different vesicle systems like ethosomes,
Unnati Garg, Karuna Jain
doaj +1 more source
Transdermal delivery of genome-editing agents by microneedle promotes the glucocorticoid therapy of inflammatory skin disorders. We report a dissolvable microneedle (MN) patch that can mediate transdermal codelivery of CRISPR-Cas9–based genome-editing ...
Tao Wan, Qi Pan, Y. Ping
semanticscholar +1 more source
Microneedles: A smart approach and increasing potential for transdermal drug delivery system.
The most widely used methods for transdermal administration of the drugs are hypodermic needles, topical creams, and transdermal patches. The effect of most of the therapeutic agents is limited due to the stratum corneum layer of the skin, which serves ...
Tejashree Waghule +6 more
semanticscholar +1 more source
The aim of this study is to design and evaluate a transdermal delivery system for alendronate sodium (ALS) loaded with nanocarrier to improve its permeability and prolong its release.
Ahlam Zaid Alkilani +5 more
doaj +1 more source
Stimuli-responsive transdermal microneedle patches
Microneedle (MN) patches consisting of miniature needles have emerged as a promising tool to perforate the stratum corneum and translocate biomolecules into the dermis in a minimally invasive manner.
Pooyan Makvandi +14 more
semanticscholar +1 more source
Objective: In order to improve patient compliance and the ease of use during progesterone application, and to increase the clinical application of progesterone, progesterone was made into a microneedle. Methods: Progesterone complexes were prepared using
Hongji He +6 more
doaj +1 more source
Optimization of Influential Variables in the Development of Buprenorphine and Bupivacaine Loaded Invasome for Dermal Delivery [PDF]
Purpose: Hydrophilic drugs are extensively applied in clinical applications. Inadequate dermal penetration of these drugs is a great challenge. Incorporation of drugs into nano-carrier systems overcomes lower penetration drawbacks.
Soraya Babaie +5 more
doaj +1 more source
The Transdermal Delivery of Therapeutic Cannabinoids
Recently, several studies have indicated an increased interest in the scientific community regarding the application of Cannabis sativa plants, and their extracts, for medicinal purposes.
Haleh Mahmoudinoodezh +5 more
doaj +1 more source

