Results 41 to 50 of about 110,346 (342)

Three-Dimensional (3D) Printed Microneedles for Microencapsulated Cell Extrusion [PDF]

open access: yes, 2018
Cell-hydrogel based therapies offer great promise for wound healing. The specific aim of this study was to assess the viability of human hepatocellular carcinoma (HepG2) cells immobilized in atomized alginate capsules (3.5% (w/v) alginate, d = 225 µm ...
Bouzos, Evangelia   +6 more
core   +3 more sources

Continuous Drug Release by Sea Anemone Nematostella vectensis Stinging Microcapsules

open access: yesMarine Drugs, 2014
Transdermal delivery is an attractive option for drug delivery. Nevertheless, the skin is a tough barrier and only a limited number of drugs can be delivered through it. The most difficult to deliver are hydrophilic drugs.
Yossi Tal   +5 more
doaj   +1 more source

Transdermal Delivery of Drugs with Microneedles—Potential and Challenges

open access: yesPharmaceutics, 2015
Transdermal drug delivery offers a number of advantages including improved patient compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect.
Kevin Ita
doaj   +1 more source

A two-phase two-layer model for transdermal drug delivery and percutaneous absorption

open access: yes, 2014
One of the promising frontiers of bioengineering is the controlled release of a therapeuticdrug from a vehicle across the skin (transdermal drug delivery).
de Monte, Filippo, Pontrelli, Giuseppe
core   +1 more source

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

open access: yes, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core   +1 more source

TRANSDERMAL NITROGLYCERIN

open access: yesThe Lancet, 1984
The Lancet 324 (1984) 990-990. doi:10.1016/S0140-6736(84)91214-5 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:21:14 ; DOI:10.1016/S0140-6736(84)91214-5 ; Page Range: 990 ...
Division of Clinical Pharmacokinetics, J. Hillis Miller Health Center, University of Florida, Gainesville, Florida 32610, U.S.A. ( host institution )   +1 more
openaire   +3 more sources

Solid Microneedles for Transdermal Delivery of Amantadine Hydrochloride and Pramipexole Dihydrochloride

open access: yesPharmaceutics, 2015
The aim of this project was to study the influence of microneedles on transdermal delivery of amantadine hydrochloride and pramipexole dihydrochloride across porcine ear skin in vitro.
Mylien T. Hoang   +2 more
doaj   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann   +6 more
wiley   +1 more source

Non-invasive transdermal delivery of biomacromolecules with fluorocarbon-modified chitosan for melanoma immunotherapy and viral vaccines

open access: yesNature Communications
Transdermal drug delivery has been regarded as an alternative to oral delivery and subcutaneous injection. However, needleless transdermal delivery of biomacromolecules remains a challenge.
Wenjun Zhu   +11 more
doaj   +1 more source

The effect of transdermal flunixin meglumine on blood cortisol levels in dairy calves after cautery disbudding with local anesthesia

open access: yesJournal of Dairy Science, 2022
: The objective of this study was to evaluate the effect of the nonsteroidal anti-inflammatory drug transdermal flunixin meglumine (Finadyne Transdermal) on plasma cortisol, average daily weight gain, and standing and lying behavior of calves, when given
M. Röder   +5 more
doaj   +1 more source

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