Results 41 to 50 of about 81,011 (193)

Polymeric microneedle-mediated transdermal delivery of melittin for rheumatoid arthritis treatment.

open access: yesJournal of Controlled Release, 2021
Transdermal drug delivery systems for rheumatoid arthritis (RA) have been receiving increasing attention as they can potentially overcome drawbacks which exist in traditional oral or injection strategies, including low patient compliance and serious ...
G. Du   +7 more
semanticscholar   +1 more source

Development of a Topical Resveratrol Formulation for Commercial Applications Using Dendrimer Nanotechnology

open access: yesMolecules, 2017
Resveratrol (RSV) is well known for its anti-oxidant and anti-aging properties. However, resveratrol is insoluble in water and has stability issues. Recently, efforts were placed to prepare a resveratrol-based advanced anti-aging topical product but it ...
Tyler Pentek   +3 more
doaj   +1 more source

Effects of transdermal versus oral hormone replacement therapy in postmenopause: a systematic review

open access: yesArchives of Gynecology and Obstetrics, 2022
Purpose To summarize available evidence comparing the transdermal and the oral administration routes of hormone replacement therapy (HRT) in postmenopausal women.
Marina Sprem Goldstajn   +9 more
semanticscholar   +1 more source

Angiotensin-Neprilysin Inhibitor Therapy: A Retrospective Chart Study

open access: yesINNOVATIONS in Pharmacy
Background: Guideline-directed medical therapy in patients with systolic heart failure (HF) has demonstrated improvement in morbidity and mortality rates.
Roda Plakogiannis   +3 more
doaj   +1 more source

Physiologically-based pharmacokinetic simulations in pharmacotherapy: selection of the optimal administration route for exogenous melatonin

open access: yesADMET and DMPK, 2019
The benefits of melatonin on human body are drawing increasing attention from several researchers in different fields. While its role as cure for sleep disturbances (e.g., jet lag, insomnia) is well documented and established, new functions in ...
Adriana Savoca, Davide Manca
doaj   +1 more source

Design, Development, and Evaluation of Treprostinil Embedded Adhesive Transdermal Patch

open access: yesPharmaceutics, 2023
Clinical application of treprostinil in pulmonary arterial hypertension is hampered by adverse effects caused by its high dosing frequency. The objective of this investigation was to Formulate an adhesive-type transdermal patch of treprostinil and ...
Ibrahim Alissa   +7 more
doaj   +1 more source

Current trends in polymer microneedle for transdermal drug delivery

open access: yesInternational journal of pharmaceutics, 2020
Graphical abstract Polymer microneedle promotes the delivery of chemical and biological drugs through the skin.
Khater Ahmed Saeed AL-Japairai   +6 more
semanticscholar   +1 more source

Development of Topical/Transdermal Self-Emulsifying Drug Delivery Systems, Not as Simple as Expected

open access: yesScientia Pharmaceutica, 2020
Self-emulsifying drug delivery systems (SEDDSs) originated as an oral lipid-based drug delivery system with the sole purpose of improving delivery of highly lipophilic drugs.
Daniélle van Staden   +2 more
doaj   +1 more source

Transdermal buprenorphine for pain management in children

open access: yesDrugs in Context, 2021
Pain is one of the main symptoms reported by sick children, particularly by those suffering from cancer. Opioids are very useful in controlling this symptom but they are burdened with significant side effects that limit their use in children ...
Giorgio Attinà   +5 more
doaj   +1 more source

Long-acting transdermal drug delivery formulations: Current developments and innovative pharmaceutical approaches.

open access: yesAdvanced Drug Delivery Reviews
Transdermal administration remains an active research and development area as an alternative route for long-acting drug delivery. It avoids major drawbacks of conventional oral (gastrointestinal side effects, low bioavailability, and multiple dosing) or ...
Tanvi Karve   +5 more
semanticscholar   +1 more source

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