Results 21 to 30 of about 23,063 (265)
Iontophoresis-driven microneedle patch for the active transdermal delivery of vaccine macromolecules
Microsystems & Nanoengineering, 2023 COVID-19 has seriously threatened public health, and transdermal vaccination is an effective way to prevent pathogen infection. Microneedles (MNs) can damage the stratum corneum to allow passive diffusion of vaccine macromolecules, but the delivery ...
Ying Zheng +8 more
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Drug Delivery, 2017 Topical and transdermal drug delivery has great potential in non-invasive and non-oral administration of poorly bioavailable therapeutic agents. However, due to the barrier function of the stratum corneum, the drugs that can be clinically feasible ...
Ki-Taek Kim +10 more
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Development of Topical/Transdermal Self-Emulsifying Drug Delivery Systems, Not as Simple as Expected
Scientia Pharmaceutica, 2020 Self-emulsifying drug delivery systems (SEDDSs) originated as an oral lipid-based drug delivery system with the sole purpose of improving delivery of highly lipophilic drugs.
Daniélle van Staden +2 more
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Plant Exosome-like Nanoparticles as Biological Shuttles for Transdermal Drug Delivery
Bioengineering, 2023 Exosomes act as emerging transdermal drug delivery vehicles with high deformability and excellent permeability, which can be used to deliver various small-molecule drugs and macromolecular drugs and increase the transdermal and dermal retention of drugs,
Ye Wang +6 more
doaj +1 more source
Pharmaceutics, 2021 Insulin is used for the treatment of diabetes mellitus, which is characterized by hyperglycemia. Subcutaneous injections are the standard mode of delivery for insulin therapy; however, this procedure is very often invasive, which hinders patient ...
Abdul Ahad +4 more
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Novel chemical permeation enhancers for transdermal drug delivery
Asian Journal of Pharmaceutical Sciences, 2014 Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, decreased side effect, easy use and better patient compliance.
Yang Chen +4 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 The transdermal route of administration provides numerous advantages over conventional routes i.e., oral or injectable for the treatment of different diseases and cosmetics applications.
Yi-Qun Yu +4 more
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Transdermal Delivery Systems for Biomolecules [PDF]
Journal of Pharmaceutical Innovation, 2021 The present review article focuses on highlighting the main technologies used as tools that improve the delivery of transdermal biomolecules, addressing them from the point of view of research in the development of transdermal systems that use physical and chemical permeation enhancers and nanocarrier systems or a combination of them.Transdermal drug ...
Ma. Concepción Peña-Juárez +2 more
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Future Journal of Pharmaceutical Sciences, 2021 Background Transdermal delivery of drugs is a quite challenging task for pharmaceutical scientists. The transdermal route is preferred over the oral route due to various advantages like avoidance of the first-pass effect, non-invasiveness, and high ...
Lalit Kumar +4 more
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Transdermal Delivery of Ketorolac
YAKUGAKU ZASSHI, 2009 A reservoir type transdermal patch for delivery of ketorolac, a potent analgesic agent was studied. The low permeability of skin is the rate-limiting step for delivery of most of the drugs. Studies were carried out to investigate the effect of permeation enhancers on the in vitro permeation of ketorolac across rat skin.
AMRISH, Chandra, KUMAR, Sharma Pramod
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