Results 141 to 150 of about 25,608 (312)

Assessment of basic pharmacokinetic parameters of dapagliflozin in TTS formulations in male minipigs

open access: yesScientific Reports
Given the extended time over which diabetes treatment is administered, the transdermal delivery system is anticipated to be a more suitable option for older individuals who may experience difficulty swallowing.
Biernat Paweł   +6 more
doaj   +1 more source

Core–Shell Silk Fibroin Hydrogel Microneedles Functionalized with Antibody-Binding Domains for Transdermal Delivery

open access: yesBiomimetics
Microneedle (MN) patches comprise a promising platform for transdermal delivery of macromolecular therapeutics. However, achieving sufficient mechanical strength for skin penetration while maintaining high biocompatibility and efficient antibody loading ...
Min Ki Lee, Ae Sol Lee, Chang Sup Kim
doaj   +1 more source

Manufacturing of a Transdermal Patch in 3D Printing. [PDF]

open access: yesMicromachines (Basel), 2022
Villota I   +4 more
europepmc   +1 more source

Antimuscarinic delirium in a pediatric patient reversed with transdermal rivastigmine: A case report

open access: yesJEM Reports
Background: Antidotal treatment of antimuscarinic delirium (AMD) standardly involves parenteral administration of physostigmine. However, due to cessation of physostigmine production, administration of oral or transdermal rivastigmine may serve as a ...
Natalie E. Ebeling-Koning   +5 more
doaj   +1 more source

Inferring rheumatoid arthritis disease activity status from the electronic health records across health systems

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Disease activity plays a central role in rheumatoid arthritis (RA) clinical studies. The inconsistent availability of data on disease activity in real‐world electronic health records (EHR) data has limited the ability to generate real‐world evidence (RWE). This study aimed to develop and validate scalable machine learning (ML) models to infer
David Cheng   +34 more
wiley   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari   +2 more
wiley   +1 more source

مقايسه اثربخشی چسب فنتانيل بين جلدی در درمان درد مزمن بيماران مبتلا به سرطان بافت نرم در مقايسه با دارونما در يک کارآزمايی بالينی تصادفی شده دو سوکور [PDF]

open access: yes, 2009
زمينه و هدف: درد ناشی از بدخيمی‌ها يکی از مشکلات عمده در بيماران مبتلا به بدخيمی به شمار می‌رود. روش‌های مختلفی تاکنون برای درمان درد مزمن ناشی از سرطان معرفی شده که مهم‌ترين آن‌ها استفاده از اپيوييدهاست.
حسنی, ولی‌الله   +4 more
core  

REVIEW: TRANSDERMAL PATCH

open access: yesInternational Journal of Biology, Pharmacy and Allied Sciences, 2021
openaire   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

open access: yesBMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang   +8 more
wiley   +1 more source

Preparation of a ligustrazine ethosome patch and its evaluation in vitro and in vivo

open access: yesInternational Journal of Nanomedicine, 2011
Xingyan Liu1, Hong Liu1, Jianqiang Liu2, Zhiwei He1, Congcong Ding1, Guoliang Huang1, Weihua Zhou3, Leshan Zhou31China-America Cancer Research Institute, of Guangdong Medical College, 2School of Pharmacy, Guangdong Medical College, Dongguan, Guangdong ...
Xingyan Liu1 Hong Liu   +3 more
doaj  

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