Results 131 to 140 of about 25,608 (312)

Autonomous AI‐Driven Design for Skin Product Formulations

open access: yesAdvanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang   +5 more
wiley   +1 more source

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin   +2 more
wiley   +1 more source

Triangulating Abuse Liability Assessment for Flavoured Cigar Products Using Physiological, Behavioural Economic and Subjective Assessments: A Within-subjects Clinical Laboratory Protocol [PDF]

open access: yes, 2018
Introduction In the USA, Food and Drug Administration regulations prohibit the sale of flavoured cigarettes, with menthol being the exception. However, the manufacture, advertisement and sale of flavoured cigar products are permitted.
Barnes, Andrew J.   +9 more
core   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen   +10 more
wiley   +1 more source

Histopathologic evaluation of skin wound healing due to local application of transdermal chitosan patch in combination with doxycycline, zinc nanoparticles, and selenium nanoparticles in mice

open access: yesBMC Veterinary Research
Background The aim of this study is to compare the histopathological changes in experimental skin wound healing in mice treated with a topical application of chitosan combined with doxycycline, as well as zinc and selenium nanoparticles.
Pegah Khosravian   +3 more
doaj   +1 more source

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

open access: yesAdvanced NanoBiomed Research, EarlyView.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo   +7 more
wiley   +1 more source

Characteristics of Analgesic Patch Formulations

open access: yesJournal of Pain Research, 2020
Srinivas Nalamachu,1,2 Jeffrey Gudin3,4 1Mid America PolyClinic, Overland Park, KS, USA; 2Kansas City University of Medicine and Biosciences, Kansas City, MO, USA; 3Department of Anesthesiology and Pain Management, Englewood Hospital and Medical Center ...
Nalamachu S, Gudin J
doaj  

Transdermal hyoscine—timing of patch [PDF]

open access: yesAnaesthesia, 1993
C M, Kumar, K, Lawler, S, Knott
openaire   +2 more sources

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

open access: yesAdvanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei   +2 more
wiley   +1 more source

The Effects of Applied Local Heat on Transdermal Drug Delivery Systems

open access: yes, 2008
Transdermal drug delivery systems have been developed over the past several decades and now include patches for birth control, nicotine addiction, and pain relief.
Holmberg, Karin   +3 more
core  

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