Results 151 to 160 of about 25,608 (312)

Radial capacity and hemodynamics evaluation in vitro and implantable feasibility validation in vivo of thinner bioresorbable polymer vascular stents

open access: yesBMEMat, EarlyView.
A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen   +9 more
wiley   +1 more source

Buprenorphine plasma and cerebrospinal fluid concentrations in osteoarthritis patients during low-dose transdermal patch dosing. [PDF]

open access: yesEur J Clin Pharmacol, 2023
Härkänen L   +7 more
europepmc   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

open access: yesBMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing   +6 more
wiley   +1 more source

Intravascular Lithotripsy Is Associated With Superior Clinical Outcomes Compared to Atherectomy: A Large‐Scale, Propensity‐Matched Analysis

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery disease (CAD) with severe calcification remains a growing challenge in percutaneous coronary intervention (PCI). Atherectomy (ATH) has long been used for plaque modification, whereas intravascular lithotripsy (IVL) has emerged as a promising alternative. Large‐scale comparative data on long‐term outcomes are limited.
Charles D. Miks   +3 more
wiley   +1 more source

Procedural Outcome of Modern Percutaneous Coronary Intervention in Proximal Chronic Total Occlusions

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Long‐term outcome in patients with chronic total occlusions (CTO) depends on the target vessel and proximity of the lesion. Aims To investigate of the target vessel was associated with procedural efficacy and safety in patients with proximal CTO lesions.
Emil N. Holck   +21 more
wiley   +1 more source

Transcatheter Repair of Sinus Venosus Defect Using a 12‐zig Covered Cheatham‐Platinum Stent in Large Superior Vena Cava—Right Atrium Junctions: Early Multicenter Experience

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Sinus venosus defect (SVD) is a rare congenital heart anomaly characterised by an abnormal communication between the atria, often associated with partial anomalous pulmonary venous connection (PAPVC). Traditional surgical repair carries significant risks, prompting exploration into less invasive transcatheter approaches.
Alberto Fuensalida   +7 more
wiley   +1 more source

Population Pharmacokinetics of Ticagrelor during Veno‐Arterial ECMO in Acute Coronary Syndrome: Model‐Informed Dosing Simulations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Although patients with acute coronary syndrome supported by veno‐arterial extracorporeal membrane oxygenation (VA‐ECMO) have a high risk of thrombosis and bleeding, antiplatelet pharmacology in this setting is not well defined. This prospective observational study investigated the population pharmacokinetics of ticagrelor and its active metabolite AR ...
Soyoung Kang   +9 more
wiley   +1 more source

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