Results 141 to 150 of about 585,058 (294)

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

Advanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel, Sailee Sham Lavekar, Ronak Jaisalmeria, Suki Oji, Jazmine Jayasi, Caroline Cvetkovic, Robert Krencik   +6 more
wiley   +1 more source

Amphiphilic nucleic acid conjugates for transfection of differentiated intestinal cells

, 2016
Elena Moroz
openalex   +2 more sources

Single or double transfection of angiostatin and endostatin genes affect mammary tumor growth, lung metastasis and structural and perfused vessels [PDF]

, 2001
Wai M. Liu, Dongping Hu, Lili Liang, Bruce M. Fenton, Paul Okunieff, Ivan Ding   +5 more
openalex   +1 more source

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner. [PDF]

Int J Mol Med
Wang Y, Tian Y, Yao G.
europepmc   +1 more source

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

Advanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin, Azhar Anwar, Jiehao Chen, Qinghao Sun, Likun Zhou, Jie Tang, Jingwei Guo, Linbo Yan, Yongci Chen, Feng Yin, Chen‐Yu Zhang, Zigang Li, Jizheng Ma, Liyuan Sheng, Xi Chen   +14 more
wiley   +1 more source

Discovery of three small-molecule inhibitors targeting <i>Ebolavirus</i> genome replication and transcription. [PDF]

J Gen Virol
Easton V, J McPhillie M, Barr J, Edwards T, Foster R, Fishwick C, Harris M.   +6 more
europepmc   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

Advanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí   +3 more
wiley   +1 more source

Effects of metallothionein-3 and metallothionein-1E gene transfection on proliferation, cell cycle, and apoptosis of esophageal cancer cells

, 2013
Zhukang Tian, Yizhuang Xu, Yufeng Zhang, Guanguo Ma, Ming He, Guan Wang   +5 more
openalex   +1 more source

398. Extracellular Matrix Identity and Surface Density Alter Transfection by Complexes Delivered from a Cell-Adhesive Substrate [PDF]

, 2006
Zain Bengali, Lonnie D. Shea
openalex   +1 more source

The Role of the CLIC/GEEC Endocytic Pathway for Mechanophysical Transfection of DNA. [PDF]

J Gene Med
Weaver S, Lallow EO, Kyker-Snowman K, Jhumur NC, Gulley M, Roberts CC, Shreiber DI, Lin H, Maslow JN.   +8 more
europepmc   +1 more source